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Impact of a mediterranean-inspired diet on cardiovascular disease risk factors: a randomized clinical trial

2024-07-26Journal article Open Access
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dc.contributor.authorBarbosa, Ana Rita
dc.contributor.authorPais, Sandra
dc.contributor.authorMarreiros, Ana
dc.contributor.authorCorreia, Marta
dc.date.accessioned2024-11-08T09:47:48Z
dc.date.available2024-11-08T09:47:48Z
dc.date.issued2024-07-26
dc.description.abstractCardiovascular diseases (CVDs) are the leading cause of death worldwide. This study focused on evaluating the impact of a Mediterranean-type diet combined with physical exercise on CVD risk factors of high-risk individuals. A randomized clinical trial (RCT) recruited individuals (≥50 years old) with no history of acute myocardial infarction, but with high CVD risk criteria according to the SCORE2/SCORE2 OP. Anthropometric and biochemical parameters were assessed at baseline and after 12 weeks of diet and exercise intervention. Participants were randomly assigned into 3 groups: no intervention group (Group 1a), physical exercise group (Group 1b), and physical exercise (±2 h/week) plus diet group (Group 2). Briefly, the dietary intervention was based on the principles of an isocaloric Mediterranean diet (MD), with seven main meals/week centered on plant-based foods (legumes and pulses). The combined effect of exercise and the diet showed significant decrease in WC (p = 0.002), BST (p < 0.001), visceral fat (p < 0.001), and TG (p = 0.029), compared with control groups. The intervention significantly increased legume intake (p < 0.001), as well as adherence to the MD, which associates with WC decrease (p = 0.024) and visceral fat (p = 0.017). A combined intervention of exercise and diet should be endorsed as an efficient modifier of cardiometabolic parameters.eng
dc.identifier.doi10.3390/nu16152443
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/10400.1/26228
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relation.ispartofNutrients
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectMediterranean diet
dc.subjectCardiovascular risk factors
dc.subjectPlanetarian diet
dc.subjectVisceral fat
dc.subjectWaist circumference
dc.subjectRandomized clinical trial
dc.titleImpact of a mediterranean-inspired diet on cardiovascular disease risk factors: a randomized clinical trialeng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue15
oaire.citation.startPage2443
oaire.citation.titleNutrients
oaire.citation.volume16
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNamePais
person.familyNameMarreiros
person.givenNameSandra
person.givenNameAna
person.identifier.ciencia-id1F1A-ED3C-3260
person.identifier.ciencia-id9A12-9450-7051
person.identifier.orcid0000-0001-8472-4994
person.identifier.orcid0000-0001-9410-4772
person.identifier.scopus-author-id56469150800
person.identifier.scopus-author-id57194785077
relation.isAuthorOfPublicationcc90b4e2-ac8a-41d3-afff-7e5d5392bfb7
relation.isAuthorOfPublicationc0a8e5da-26ae-42a8-ab04-fa4df4356375
relation.isAuthorOfPublication.latestForDiscoveryc0a8e5da-26ae-42a8-ab04-fa4df4356375

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