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Publicação
Shedding light on the hidden benefit of Porphyridium cruentum culture
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Orientador(es)
Resumo(s)
Microalgae can represent a reliable source of natural compounds with different activities.
Here, we evaluated the antioxidant and anti-inflammatory activity of sulfated exopolysaccharides
(s-EPSs) and phycoerythrin (PE), two molecules naturally produced by the red marine microalga
Porphyridium cruentum (CCALA415). In vitro and cell-based assays were performed to assess the
biological activities of these compounds. The s-EPSs, owing to the presence of sulfate groups, showed
biocompatibility on immortalized eukaryotic cell lines and a high antioxidant activity on cell-based
systems. PE showed powerful antioxidant activity both in vitro and on cell-based systems, but
purification is mandatory for its safe use. Finally, both molecules showed anti-inflammatory activity
comparable to that of ibuprofen and helped tissue regeneration. Thus, the isolated molecules from
microalgae represent an excellent source of antioxidants to be used in different fields.
Descrição
Palavras-chave
Microalgae Exopolysaccharides Phycoerythrin Antioxidant activity Anti-inflammatory activity Biocompatibility Wound healing
Contexto Educativo
Citação
Antioxidants 12 (2): 337 (2023)
Editora
MDPI