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Enhancing therapy with nano-based delivery systems: exploring the bioactive properties and effects of apigenin

2024-09Artigo científico Acesso restrito
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datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorKumar, Girish
dc.contributor.authorJain, Pushpika
dc.contributor.authorVirmani, Tarun
dc.contributor.authorSharma, Ashwani
dc.contributor.authorAkhtar, Md Sayeed
dc.contributor.authorAldosari, Saad A
dc.contributor.authorKhan, Mohd Faiyaz
dc.contributor.authorDuarte, Sofia O D
dc.contributor.authorFonte, Pedro
dc.date.accessioned2026-05-07T13:21:57Z
dc.date.available2026-05-07T13:21:57Z
dc.date.issued2024-09
dc.description.abstractApigenin, a poten t na tural flav onoid , has emerged as a key therapeutic agent due to its multifac et ed medicinal properties in combating various diseases. How ev er, apigenin’s clinical utility is greatly limited by its poor w a ter solubility, low bioav ailabilit y and stabilit y issues. To address these challenges, this review paper explores the innov a tive field of nanotechnology-based delivery sy st ems, which have shown significant promise in improving the delivery and effectiveness of apigenin. This paper also explores the synerg istic pot ential of c o-delivering apigenin with conventional therapeutic agents. Despite the advantageous properties of these nanoformulations, critical challenges such as scalable pr oduction, r egulatory appr ovals and compr ehensiv e long-term safety assessments remain key hurdles in their clinical adoption which must be addressed for commercialization of apigenin-based formulations.eng
dc.identifier.doi10.1080/20415990.2024.2386928
dc.identifier.eissn2041-6008
dc.identifier.issn2041-5990
dc.identifier.urihttp://hdl.handle.net/10400.1/28887
dc.language.isoeng
dc.peerreviewedyes
dc.publisherInforma UK Limited
dc.relationAlgarve Centre for Marine Sciences
dc.relationAlgarve Centre for Marine Sciences
dc.relationCentre for Marine and Environmental Research
dc.relationInstitute for Bioengineering and Biosciences
dc.relationInstitute for Bioengineering and Biosciences
dc.relationInstitute for Health and Bioeconomy
dc.relation.ispartofTherapeutic Delivery
dc.rights.uriN/A
dc.subjectApigenin
dc.subjectBioavailability
dc.subjectFlavonoid
dc.subjectNanocarriers
dc.subjectPolymers
dc.subjectStability
dc.subjectTherapeutics
dc.titleEnhancing therapy with nano-based delivery systems: exploring the bioactive properties and effects of apigenineng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/04326/2020
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oaire.awardNumberUIDB/04565/2020
oaire.awardNumberUIDP/04565/2020
oaire.awardNumberLA/P/0140/2020
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleCentre for Marine and Environmental Research
oaire.awardTitleInstitute for Bioengineering and Biosciences
oaire.awardTitleInstitute for Bioengineering and Biosciences
oaire.awardTitleInstitute for Health and Bioeconomy
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oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0101%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04565%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04565%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0140%2F2020/PT
oaire.citation.issue9
oaire.citation.titleTherapeutic Delivery
oaire.citation.volume15
oaire.fundingStream6817 - DCRRNI ID
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oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameFonte
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person.identifier.ciencia-id2410-123D-3385
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