Publicação
Serum biomarkers of extracellular matrix remodeling in ulcerative colitis—one step closer to fibrosis biomarkers in inflammatory bowel disease
| datacite.subject.sdg | 03:Saúde de Qualidade | |
| datacite.subject.sdg | 09:Indústria, Inovação e Infraestruturas | |
| datacite.subject.sdg | 04:Educação de Qualidade | |
| dc.contributor.author | Sousa, Helena Tavares | |
| dc.contributor.author | de Oliveira, Raquel | |
| dc.date.accessioned | 2026-04-13T09:19:00Z | |
| dc.date.available | 2026-04-13T09:19:00Z | |
| dc.date.issued | 2025-02-13 | |
| dc.description.abstract | Fibrosis is a serious complication of both Crohn's disease (CD) and ulcerative colitis(UC) and is currently the major unmet need in inflammatory bowel disease (IBD) management [1]. Although much less prevalent in UC, strong evidence supports severity and chronicity of inflammation are the main drivers of excessive extracellular matrix (ECM) deposition in the submucosa and muscularis mucosae [2], leading to increased wall stiffness, and ultimately to motility and anorectal dysfunction, rectal urgency and incontinence. | eng |
| dc.identifier.doi | 10.1002/ueg2.12770 | |
| dc.identifier.eissn | 2050-6414 | |
| dc.identifier.issn | 2050-6406 | |
| dc.identifier.uri | http://hdl.handle.net/10400.1/28650 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | Wiley | |
| dc.relation.ispartof | United European Gastroenterology Journal | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.title | Serum biomarkers of extracellular matrix remodeling in ulcerative colitis—one step closer to fibrosis biomarkers in inflammatory bowel disease | eng |
| dc.type | editorial | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 850 | |
| oaire.citation.issue | 6 | |
| oaire.citation.startPage | 849 | |
| oaire.citation.title | United European Gastroenterology Journal | |
| oaire.citation.volume | 13 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| person.familyName | Sousa | |
| person.familyName | de Oliveira | |
| person.givenName | Helena Tavares | |
| person.givenName | Raquel | |
| person.identifier.ciencia-id | CF1F-1163-1C4A | |
| person.identifier.orcid | 0000-0002-6626-205X | |
| person.identifier.orcid | 0000-0002-3818-981X | |
| relation.isAuthorOfPublication | 6b1d11dd-486f-4fb3-b41f-02e1cf6a5c2e | |
| relation.isAuthorOfPublication | 6342394b-9f17-4e83-bacd-5e7f45bb958e | |
| relation.isAuthorOfPublication.latestForDiscovery | 6b1d11dd-486f-4fb3-b41f-02e1cf6a5c2e |
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