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The use of biomarkers to assess the impact of pollution in coastal environments of the Iberian Peninsula: a practical approach

2000Journal article Restricted access
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dc.contributor.authorCajaraville, Miren P.
dc.contributor.authorBebianno, Maria João
dc.contributor.authorBlasco, Julián
dc.contributor.authorPorte, Cinta
dc.contributor.authorSarasquete, Carmen
dc.contributor.authorViarengo, Aldo
dc.date.accessioned2020-06-04T12:09:55Z
dc.date.available2020-06-04T12:09:55Z
dc.date.issued2000
dc.description.abstractWithin the frame of the 2nd Iberian Congress of Environmental Contamination and Toxicology (University of the Basque Country, Leioa, June 1998) a workshop was held about the use of biomarkers in marine pollution monitoring. Among others, the following biomarkers received special attention: metallothionein induction, acetylcholinesterase inhibition, cytochrome P450 system induction, imposer, lysosomal enlargement and lysosomal membrane destabilisation, and peroxisome proliferation. These biomarkers can be used to evaluate exposure to and effect of different contaminants (metals, organic xenobiotics and organometallic compounds) and they can be measured using different methodological approaches (biochemistry, cytochemistry, immunochemical methods based on the use of biotechnology). Before the application of a set of biomarkers in pollution monitoring programmes, well-defined protocols of Quality Assurance have to be established to allow adequate comparison of results. It is also necessary to include analysis of standard reference materials and to obtain detailed knowledge of basal values and seasonal variations of the biomarkers in various species, as well as to integrate the information obtained with the different biomarkers, Marine bivalve molluscs such as mussels are appropriate sentinel species for most of the biomarkers proposed except for the induction of the cytochrome P450 system, which should be measured in fish, and the degree of imposer, which is a biomarker of exposure to TBT specifically measured in certain gastropod molluscs. As a result of the workshop, a battery of biomarkers of contaminant exposure and effects are proposed that could be incorporated into programmes monitoring the quality of the coastal environment in the Iberian Peninsula. These measures would be undertaken in conjunction with chemical measures of contaminant burdens in selected sentinel species.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/S0048-9697(99)00499-4pt_PT
dc.identifier.issn0048-9697
dc.identifier.urihttp://hdl.handle.net/10400.1/13983
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBiomarkerspt_PT
dc.subjectEnvironmental pollution assessmentpt_PT
dc.subjectMetallothioneinpt_PT
dc.subjectAcetylcholinesterasept_PT
dc.subjectcytochrome P450 systempt_PT
dc.subjectStress enzymespt_PT
dc.titleThe use of biomarkers to assess the impact of pollution in coastal environments of the Iberian Peninsula: a practical approachpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage311pt_PT
oaire.citation.issue2-3pt_PT
oaire.citation.startPage295pt_PT
oaire.citation.titleScience of the Total Environmentpt_PT
oaire.citation.volume247pt_PT
person.familyNameBebianno
person.givenNameMaria
person.identifier.ciencia-id2B11-46AC-B94B
person.identifier.orcid0000-0003-1492-8566
person.identifier.scopus-author-id7004152715
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication2e00a26d-1dd3-4c22-a6bf-ac7943ae0d32
relation.isAuthorOfPublication.latestForDiscovery2e00a26d-1dd3-4c22-a6bf-ac7943ae0d32

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