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Acetylcholine release and choline uptake by cuttlefish (Sepia officinalis) optic lobe synaptosomes

2008-02Journal article Open access
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dc.contributor.authorNunes, M. Alexandra
dc.contributor.authorSantos, Sofia
dc.contributor.authorCordeiro, J. Miguel
dc.contributor.authorNeves, Paulo
dc.contributor.authorSilva, Virgília S.
dc.contributor.authorSykes, António V.
dc.contributor.authorMorgado, Fernando
dc.contributor.authorDunant, Yves
dc.contributor.authorGonçalves, Paula P.
dc.date.accessioned2018-11-09T15:04:03Z
dc.date.available2018-11-09T15:04:03Z
dc.date.issued2008-02
dc.description.abstractAcetylcholine (ACh), which is synthesized from choline (Ch), is believed to hold a central place in signaling mechanisms within the central nervous system (CNS) of cuttlefish (Sepia officinalis) and other coleoid cephalopods. Although the main elements required for cholinergic function have been identified in cephalopods, the transmembrane translocation events promoting the release of ACh and the uptake of Ch remain largely unsolved. The ACh release and Ch uptake were quantitatively studied through the use of in vitro chemiluminescence and isotopic methods on a subcellular fraction enriched in synaptic nerve endings (synaptosomes) isolated from cuttlefish optic lobe.pt_PT
dc.description.sponsorshipQLK1-CT-2002-00172
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.issn0006-3185
dc.identifier.urihttp://hdl.handle.net/10400.1/10920
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMarine Biological Laboratorypt_PT
dc.relationThe synaptosome as a screening tool in Ecotoxicology
dc.relationDISTRIBUIÇÃO, ESTRUTURA E FUNÇÃO DO ANTIPORTE DE CA2+/H+ DAS VESÍCULAS SINÁPTICAS NO CÉREBRO
dc.relationEFEITO DA TRANSLOCAÇÃO CATIÓNICA MEDIADA POR VESÍCULAS SINÁPTICAS NA NEUROTRANSMISSÃO
dc.relationMOLECULAR STUDY OF GENETIC CODE AMBIGUITY IN CANDIDA ALBICANS
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleAcetylcholine release and choline uptake by cuttlefish (Sepia officinalis) optic lobe synaptosomespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleThe synaptosome as a screening tool in Ecotoxicology
oaire.awardTitleDISTRIBUIÇÃO, ESTRUTURA E FUNÇÃO DO ANTIPORTE DE CA2+/H+ DAS VESÍCULAS SINÁPTICAS NO CÉREBRO
oaire.awardTitleEFEITO DA TRANSLOCAÇÃO CATIÓNICA MEDIADA POR VESÍCULAS SINÁPTICAS NA NEUROTRANSMISSÃO
oaire.awardTitleMOLECULAR STUDY OF GENETIC CODE AMBIGUITY IN CANDIDA ALBICANS
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POCI/POCTI%2FBSE%2F46721%2F2002/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F14677%2F2003/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POCTI/SFRH%2FBD%2F1079%2F2000/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F6403%2F2001/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F18101%2F2004/PT
oaire.citation.endPage5pt_PT
oaire.citation.issue214pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleBiological Bulletinpt_PT
oaire.fundingStreamPOCI
oaire.fundingStreamSFRH
oaire.fundingStreamPOCTI
person.familyNameSykes
person.givenNameAntónio
person.identifier107454
person.identifier.ciencia-id7510-6641-5A42
person.identifier.orcid0000-0002-5207-0612
person.identifier.ridC-3609-2012
person.identifier.scopus-author-id7102626426
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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