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Chemical and biochemical tools to assess pollution exposure in aquatic ecosystems

dc.contributor.advisorBebianno, Maria João da Anunciação Franco
dc.contributor.advisorVisa, Cinta Porte
dc.contributor.authorFernandes, Denise Robina Teixeira
dc.date.accessioned2011-09-07T16:05:30Z
dc.date.available2011-09-07T16:05:30Z
dc.date.issued2007
dc.descriptionTese dout., Ciências e Tecnologias do Ambiente, Universidade do Algarve, 2007por
dc.description.abstractAquatic environments offer and sustain important habitats for many fish species, but also attract an ever-increasing level of human activities. These environments are the ultimate sink for many of the chemical contaminants released from anthropogenic activities, which can represent a great threat to organisms living in these ecosystems, as to human health. In recent years, there has been a growing awareness of the need to detect and assess the adverse effects of contaminants in organisms exposed to different levels of pollutants. Among the available techniques, the integrated use of chemical analysis and biochemical responses to pollutants is a sound procedure for detecting impact of anthropogenic contaminants in aquatic systems. Besides wild fish consumption, the aquaculture industry is an expanding activity, due to the world population demand of fish however, the intensive production and the extensive use of chemicals in current practises, has raised concerns over the quality of cultured fish in comparison to wild fish. Although, both wild and cultured fish are important components of the Atlantic and Mediterranean diet, there is little information regarding pollutant levels in farmed fish and the risks associated to consumption. In the present thesis the impact of pollutants were investigated in both wild and cultured fish from different aquatic ecosystems, by the combined analysis of chemical residues in fish tissues together with biochemical responses. Specific biological responses (MT, phase I and II enzymes, CAT, AChE, Vtg) to a range of environmental stressors (metals, OCs, PAHs, APEs) were assessed in wild sea bass (Dicentrarchus labrax L.) from the Arade Estuary (S Portugal) and in cultured sea bass from different aquaculture facilities located in Southern Europe. Furthermore, the impact of pollution along the Northern Iberian coast was assessed using two commercial fish species, the four-spotted-megrim (Lepidorhombus boscii) and the pouting (Trisopterus luscus) as sentinel organisms. Finally, since the interference of xenobiotics with steroid synthesis and steroid metabolism in fish may alter the bioavailable amounts of active hormones within the organism, the metabolism of 17α-hydroxyprogesterone (17P4) in male sea bass gonads was investigated, as a potential tool for the detection of endocrine alterations in male fish, by evaluating the in vitro effect of model endocrine disrupters (NP, BaA, TBT, p,p’-DDE, KCZ)eng
dc.description.sponsorshipFundação para a Ciência e Tecnologia (FCT)por
dc.formatapplication/pdfpor
dc.identifier.other574.5 FER*Che Cave
dc.identifier.tid101155638
dc.identifier.urihttp://hdl.handle.net/10400.1/763
dc.language.isoengpor
dc.relationUTILIZAÇÃO DE BIOMARCADORES NA AVALIAÇÃO DOS EFEITOS DE CONTAMINANTES ORGÂNICOS PERSISTENTES NA DISRUPÇÃO ENDÓCRINA
dc.subjectTesespor
dc.subjectEcossistemas aquáticospor
dc.subjectPeixespor
dc.subjectBiomarcadorespor
dc.subjectPoluiçãopor
dc.subjectAquaculturapor
dc.titleChemical and biochemical tools to assess pollution exposure in aquatic ecosystemspor
dc.typedoctoral thesis
dspace.entity.typePublication
oaire.awardTitleUTILIZAÇÃO DE BIOMARCADORES NA AVALIAÇÃO DOS EFEITOS DE CONTAMINANTES ORGÂNICOS PERSISTENTES NA DISRUPÇÃO ENDÓCRINA
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POCI-2010/SFRH%2FBD%2F6123%2F2001/PT
oaire.fundingStreamPOCI-2010
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typedoctoralThesispor
relation.isProjectOfPublication0c2dbd48-7361-4fd3-a228-246d2f10286b
relation.isProjectOfPublication.latestForDiscovery0c2dbd48-7361-4fd3-a228-246d2f10286b
thesis.degree.grantorUniversidade do Algarve. Faculdade de Ciências do Mar e do Ambientepor
thesis.degree.levelDoutorpor
thesis.degree.nameDoutoramento em Ciências e Tecnologias do Ambientepor

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