Publication
Chemical and biochemical tools to assess pollution exposure in aquatic ecosystems
dc.contributor.advisor | Bebianno, Maria João da Anunciação Franco | |
dc.contributor.advisor | Visa, Cinta Porte | |
dc.contributor.author | Fernandes, Denise Robina Teixeira | |
dc.date.accessioned | 2011-09-07T16:05:30Z | |
dc.date.available | 2011-09-07T16:05:30Z | |
dc.date.issued | 2007 | |
dc.description | Tese dout., Ciências e Tecnologias do Ambiente, Universidade do Algarve, 2007 | por |
dc.description.abstract | Aquatic environments offer and sustain important habitats for many fish species, but also attract an ever-increasing level of human activities. These environments are the ultimate sink for many of the chemical contaminants released from anthropogenic activities, which can represent a great threat to organisms living in these ecosystems, as to human health. In recent years, there has been a growing awareness of the need to detect and assess the adverse effects of contaminants in organisms exposed to different levels of pollutants. Among the available techniques, the integrated use of chemical analysis and biochemical responses to pollutants is a sound procedure for detecting impact of anthropogenic contaminants in aquatic systems. Besides wild fish consumption, the aquaculture industry is an expanding activity, due to the world population demand of fish however, the intensive production and the extensive use of chemicals in current practises, has raised concerns over the quality of cultured fish in comparison to wild fish. Although, both wild and cultured fish are important components of the Atlantic and Mediterranean diet, there is little information regarding pollutant levels in farmed fish and the risks associated to consumption. In the present thesis the impact of pollutants were investigated in both wild and cultured fish from different aquatic ecosystems, by the combined analysis of chemical residues in fish tissues together with biochemical responses. Specific biological responses (MT, phase I and II enzymes, CAT, AChE, Vtg) to a range of environmental stressors (metals, OCs, PAHs, APEs) were assessed in wild sea bass (Dicentrarchus labrax L.) from the Arade Estuary (S Portugal) and in cultured sea bass from different aquaculture facilities located in Southern Europe. Furthermore, the impact of pollution along the Northern Iberian coast was assessed using two commercial fish species, the four-spotted-megrim (Lepidorhombus boscii) and the pouting (Trisopterus luscus) as sentinel organisms. Finally, since the interference of xenobiotics with steroid synthesis and steroid metabolism in fish may alter the bioavailable amounts of active hormones within the organism, the metabolism of 17α-hydroxyprogesterone (17P4) in male sea bass gonads was investigated, as a potential tool for the detection of endocrine alterations in male fish, by evaluating the in vitro effect of model endocrine disrupters (NP, BaA, TBT, p,p’-DDE, KCZ) | eng |
dc.description.sponsorship | Fundação para a Ciência e Tecnologia (FCT) | por |
dc.format | application/pdf | por |
dc.identifier.other | 574.5 FER*Che Cave | |
dc.identifier.tid | 101155638 | |
dc.identifier.uri | http://hdl.handle.net/10400.1/763 | |
dc.language.iso | eng | por |
dc.relation | UTILIZAÇÃO DE BIOMARCADORES NA AVALIAÇÃO DOS EFEITOS DE CONTAMINANTES ORGÂNICOS PERSISTENTES NA DISRUPÇÃO ENDÓCRINA | |
dc.subject | Teses | por |
dc.subject | Ecossistemas aquáticos | por |
dc.subject | Peixes | por |
dc.subject | Biomarcadores | por |
dc.subject | Poluição | por |
dc.subject | Aquacultura | por |
dc.title | Chemical and biochemical tools to assess pollution exposure in aquatic ecosystems | por |
dc.type | doctoral thesis | |
dspace.entity.type | Publication | |
oaire.awardTitle | UTILIZAÇÃO DE BIOMARCADORES NA AVALIAÇÃO DOS EFEITOS DE CONTAMINANTES ORGÂNICOS PERSISTENTES NA DISRUPÇÃO ENDÓCRINA | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/POCI-2010/SFRH%2FBD%2F6123%2F2001/PT | |
oaire.fundingStream | POCI-2010 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
rcaap.rights | openAccess | por |
rcaap.type | doctoralThesis | por |
relation.isProjectOfPublication | 0c2dbd48-7361-4fd3-a228-246d2f10286b | |
relation.isProjectOfPublication.latestForDiscovery | 0c2dbd48-7361-4fd3-a228-246d2f10286b | |
thesis.degree.grantor | Universidade do Algarve. Faculdade de Ciências do Mar e do Ambiente | por |
thesis.degree.level | Doutor | por |
thesis.degree.name | Doutoramento em Ciências e Tecnologias do Ambiente | por |
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