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Identification of an RNA silencing suppressor encoded by Grapevine leafroll-associated virus 3

dc.contributor.authorGouveia, P.
dc.contributor.authorDandlen, S. A.
dc.contributor.authorCosta, A.
dc.contributor.authorMarques, N T.
dc.contributor.authorNolasco, Gustavo
dc.date.accessioned2015-06-15T14:13:46Z
dc.date.available2015-06-15T14:13:46Z
dc.date.issued2012
dc.description.abstractGLRaV-3, a member of the Closteroviridae family and type member of the genus Ampelovirus, is involved in the grapevine leafroll disease. Until now no RNA silencing suppressor has been found among viruses of this genus, contrary to what happens with a large number of other viral genera. In the sister genus Closterovirus, RNA silencing suppressors are present in the 3' end of the genome and have molecular weights close to 20 KDa. To test for RNA suppressing activity screening of p21, p19.6 and p19.7 proteins, coded for in an analogous genomic location of the GLRaV-3 was undertaken. Only p19.7 revealed suppressor activity demonstrated in diverse silencing inducing systems. This suppressor is able to overcome strong silencing inducers and shares several properties with the BYV p21-like family of suppressors of the closteroviruses. This is the first report of an RNA silencing suppressor in the genus Ampelovirus.
dc.identifier.doihttps://dx.doi.org/10.1007/s10658-011-9876-1
dc.identifier.issn0929-1873
dc.identifier.otherAUT: GNO00324;
dc.identifier.urihttp://hdl.handle.net/10400.1/6239
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer
dc.relation.isbasedonP-002-ARR
dc.titleIdentification of an RNA silencing suppressor encoded by Grapevine leafroll-associated virus 3
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage245
oaire.citation.startPage237
oaire.citation.titleEuropean Journal of Plant Pathology
oaire.citation.volume133
person.familyNameTomás Marques
person.familyNameNolasco
person.givenNameNatália
person.givenNameGustavo
person.identifier.ciencia-id1510-CD2F-81CE
person.identifier.orcid0000-0002-0222-621X
person.identifier.orcid0000-0002-7025-6023
person.identifier.scopus-author-id6602625528
rcaap.rightsrestrictedAccess
rcaap.typearticle
relation.isAuthorOfPublication4b1751aa-958b-4d68-ae97-ea628673ba00
relation.isAuthorOfPublication87a8035f-bc15-44dd-b8c3-4288c5660fff
relation.isAuthorOfPublication.latestForDiscovery87a8035f-bc15-44dd-b8c3-4288c5660fff

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