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Cloning of the Bone Gla Protein gene from the teleost fish Sparus aurata (gilthead seabream). Molecular organization, developmental appearance and evolutionary implications

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Abstract(s)

A proteína Bone Gla (BGP, osteocalcina) é uma pequena proteína dependenteda. vitamina K que apresenta resíduos de ácido glutâmico y-carboxilados. A presença destes aminoácidos modificados permite à proteína ligar-se a iões Ca2+ e interagir com os cristais de hidroxiapatite dos tecidos mineralizados.
The Bone Gla Protein (BGP, osleocalcin) is a small vilamin K-dependent protein which presenls Ihree y-carboxylated glutamic acid residues. lhe prcsence oí these modified amino acids enables the protein to bind to Ca2+ ions and to interact with hydroxyapatite ciystals of mineralized tissues.

Description

Tese de Doutoramento, Biologia Molecular, Faculdade de Ciências do Mar e do Ambiente, Universidade do Algarve, 2001

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Bone Gla-proteína

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