Logo do repositório
 
Publicação

A multidirectional study on chemical fingerprints and biological activities of three Cistus extracts (C. creticus, C. laurifolius, and C. salviifolius) with ethnomedicinal uses

2024-11-13Artigo científico Acesso aberto
Ver registo simples
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorYagi, Sakina
dc.contributor.authorZengin, Gökhan
dc.contributor.authorSELVİ, Selami
dc.contributor.authorAK, Güneş
dc.contributor.authorCZIÁKY, Zoltán
dc.contributor.authorJekő, József
dc.contributor.authorRodrigues, Maria João
dc.contributor.authorCustódio, Luísa
dc.contributor.authorVenanzoni, Roberto
dc.contributor.authorFlores, Giancarlo Angeles
dc.contributor.authorCusumano, Gaia
dc.contributor.authorANGELINI, Paola
dc.date.accessioned2026-05-05T09:15:30Z
dc.date.available2026-05-05T09:15:30Z
dc.date.issued2024-11-13
dc.description.abstractHumans have used medicinal plants to treat various diseases for thousands of years. Cistus species are also widely used in traditional medicine and have various medicinal applications; therefore, they deserve more in-depth research. The present study evaluated the chemical profile, antioxidant, enzyme inhibition, and cytotoxic properties of the twigs and leaves of C. creticus L., C. laurifolius L., and C. salviifolius L. grown in Türkiye. The methanolic extracts of the three species were rich in phenolics, mainly flavonoids. Exerted potent antioxidant activity with a methanolic extract from the leaves of C. salviifolius displayed the highest total phenolic (97.08-mg gallic acid equivalent/g) and flavonoid (49.60-mg rutin equivalent/g) contents, as well as antiradical (2,2-diphenyl-1-picrylhydrazyl) assay = 612.11 mg TE (trolox equivalent)/g; (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) = 804.66 mg TE/g), reducing ions (cupric reducing antioxidant capacity) = 690.54 mg TE/g; ferric reducing antioxidant power = 459.34 mg TE/g), and chelating (15.58 mg EDTAE/g) properties. It also revealed the best amylase and glucosidase inhibitory activity. Extracts from the twigs of the three Cistus species, except the leaves of C. salviifolius and C. laurifolius, displayed comparable acetylcholinesterase inhibitory activity (2.48–2.57 mg galanthamine equivalent (GALAE)/g). The twig of C. laurifolius also exerted the best antibutyrylcholinesterase (10.50 mg GALAE/g) and antityrosinase (73.15 mg kojic acid equivalent/g) activities. C. creticus leaves revealed toxicity toward the RAW cell line (cell viability reduced to 68.8%) and were not toxic to normal cells (S17). In conclusion, these three Cistus species were shown to be a rich source of bioactive compounds with the potential for future applications in the food, pharmaceutical, and cosmetic industries.eng
dc.identifier.doi10.55730/1300-008x.2820
dc.identifier.issn1300-008X
dc.identifier.urihttp://hdl.handle.net/10400.1/28847
dc.language.isoeng
dc.peerreviewedyes
dc.publisherThe Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS
dc.relationAlgarve Centre for Marine Sciences
dc.relationAlgarve Centre for Marine Sciences
dc.relationCentre for Marine and Environmental Research
dc.relation.ispartofTurkish Journal of Botany
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCistus species
dc.subjectEthnomedicinal
dc.subjectAntioxidant
dc.subjectEnzyme inhibition
dc.subjectCytotoxicity
dc.titleA multidirectional study on chemical fingerprints and biological activities of three Cistus extracts (C. creticus, C. laurifolius, and C. salviifolius) with ethnomedicinal useseng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/04326/2020
oaire.awardNumberUIDP/04326/2020
oaire.awardNumberLA/P/0101/2020
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleCentre for Marine and Environmental Research
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0101%2F2020/PT
oaire.citation.endPage337
oaire.citation.issue6
oaire.citation.startPage321
oaire.citation.titleTurkish Journal of Botany
oaire.citation.volume48
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameRodrigues
person.familyNameCustódio
person.givenNameMaria João
person.givenNameLuísa
person.identifierR-004-VNG
person.identifier.ciencia-id2514-0E17-1D8D
person.identifier.ciencia-id791B-C560-AEA2
person.identifier.orcid0000-0001-8732-710X
person.identifier.orcid0000-0003-4338-7703
person.identifier.ridM-6101-2013
person.identifier.scopus-author-id56031608100
person.identifier.scopus-author-id15831018900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublication12c32925-de9e-4289-bdd5-1d655d7a278c
relation.isAuthorOfPublicationf9cfed0f-6b67-413e-988c-ac7397183471
relation.isAuthorOfPublication.latestForDiscovery12c32925-de9e-4289-bdd5-1d655d7a278c
relation.isProjectOfPublicationfafa76a6-2cd2-4a6d-a3c9-772f34d3b91f
relation.isProjectOfPublication15f91d45-e070-47d8-b6b8-efd4de31d9a8
relation.isProjectOfPublication794d4c77-c731-471e-bc96-5a41dcd3d872
relation.isProjectOfPublication.latestForDiscoveryfafa76a6-2cd2-4a6d-a3c9-772f34d3b91f

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
A multidirectional study on chemical fingerprints and biological.pdf
Tamanho:
1 MB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
3.46 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

CCM2-Artigos (em revistas ou actas indexadas)