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Association of milk traits with SSCP polymorphisms at the growth hormone gene in the Serrana goat

2003Journal article Restricted access
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dc.contributor.authorMarques, P. X.
dc.contributor.authorPereira, M.
dc.contributor.authorMarques, MR
dc.contributor.authorSantos, Ingrid
dc.contributor.authorBelo, Carmona
dc.contributor.authorRenaville, Robert
dc.contributor.authorCravador, A.
dc.date.accessioned2012-06-09T10:53:06Z
dc.date.available2012-06-09T10:53:06Z
dc.date.issued2003
dc.date.updated2012-05-24T19:57:05Z
dc.description.abstractThe present study suggests the existence of an association between milk production traits and genetic polymorphisms at the growth hormone (GH) gene in the Portuguese indigenous Serrana goat. TheDNAfrom 229 animals of two ecotypes (Jarmelista and Ribatejano)was analysed by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique revealing a high degree of genetic polymorphism at the goat GH (gGH) gene. Two conformation patterns were detected in exons 1 and 2, 6 in exon 3, 10 in exon 4 and 5 in exon 5. The evaluation of an association effect between these SSCP patterns with milk, fat and protein yields and fat and protein percentages suggests a positive effect of pattern A/B of exon 4 for Ribatejano ecotype and of pattern A/B of exon 2 for Jarmelista ecotype with milk yield (P < 0.05) and of pattern A/B of exon 1 and pattern B/B of exon 2 with protein percentage (P < 0.05) for Ribatejano ecotype. The results support the hints suggested by previous studies of the importance of the gGH gene as a candidate gene for marker-assisted selection in goat breeds and suggest that exon 4 is a preferential target for further investigation on mutations that influence milk yield variation.por
dc.identifier.citationMarques, P. X.; Pereira, M.; Marques, M. Rosário; Santos, Ingrid; Belo, Carmona; Renaville, Robert; Cravador, Alfredo. Association of milk traits with SSCP polymorphisms at the growth hormone gene in the Serrana goat. Small Ruminant Research, 50, 1-2, 177-185, 2003.por
dc.identifier.issn0921-4488
dc.identifier.otherAUT: ACR00659;
dc.identifier.urihttp://hdl.handle.net/10400.1/1219
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectSingle strand conformation polymorphismpor
dc.subjectGenetic markerspor
dc.subjectGrowth hormonepor
dc.subjectGoatpor
dc.subjectMilk traitspor
dc.titleAssociation of milk traits with SSCP polymorphisms at the growth hormone gene in the Serrana goatpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage185por
oaire.citation.issue50(1-2)por
oaire.citation.startPage177por
oaire.citation.titleSmall Ruminant Researchpor
person.familyNameMarques
person.familyNameCravador
person.givenNameMaria do Rosário
person.givenNameAlfredo
person.identifier.ciencia-id0118-8469-A3DF
person.identifier.orcid0000-0002-5981-3829
person.identifier.orcid0000-0002-9831-9815
person.identifier.ridK-7247-2012
person.identifier.scopus-author-id15044877200
person.identifier.scopus-author-id6602537257
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication8dc3c7f1-5d0c-44be-a0b7-f6c3315c87dc
relation.isAuthorOfPublication8c84a9e6-6b7f-4b50-93a2-152c85901722
relation.isAuthorOfPublication.latestForDiscovery8dc3c7f1-5d0c-44be-a0b7-f6c3315c87dc

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