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The influence of in vitro gastrointestinal digestion on the chemical composition and antioxidant and enzyme inhibitory capacities of carob liqueurs obtained with different elaboration techniques

2019Journal article Open access
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dc.contributor.authorRodríguez Solana, Raquel
dc.contributor.authorCoelho, Natacha
dc.contributor.authorSantos-Rufo, Antonio
dc.contributor.authorGonçalves, Sandra
dc.contributor.authorPérez-Santín, Efrén
dc.contributor.authorRomano, Anabela
dc.date.accessioned2020-02-05T15:24:04Z
dc.date.available2020-02-05T15:24:04Z
dc.date.issued2019
dc.description.abstractCarob liqueur is a traditional Mediterranean alcoholic beverage obtained via a wide range of production techniques contributing to the different organoleptic attributes of the final product. The aim of this research was to evaluate the stability of the chemical composition and biological capacities (antioxidant and enzyme inhibition) under in vitro simulated gastrointestinal digestion of liqueurs prepared by flavouring the fig spirit with carob pulp by maceration, distillation, percolation, or aqueous and hydro-alcoholic infusions. For this purpose, the phenolic and furanic compositions, the total phenolic (TPC) and flavonoid (TFC) contents, antioxidant capacity (AC), and enzyme inhibitory potential against acethylcholinesterase, tyrosinase, α-glucosidase and α-amylase enzymes were evaluated. The content of gallic acid decreased after gastrointestinal digestion, while TPC, TFC, and AC significantly increased after each digestion phase. Overall, no significantly different enzyme inhibitions (p < 0.05) were observed among digested liqueurs, with moderate inhibition against acethylcholinesterase and tyrosinase (enzymes related with neurodegenerative diseases), and potent and low inhibitory capacities for α-glucosidase and α-amylase, respectively (ideal conditions employed in antidiabetic therapy). The study indicates that hydro-alcoholic infusion and maceration were the most appropriate methods to obtain liqueurs with higher values of the aforementioned parameters and safe levels of toxic furanics.pt_PT
dc.description.sponsorshipFundação para a Ciência e a Tecnologia, I.P.: SFRH/BPD/103086/2014; DL 57/2016/CP1361/CT0022; project INTERREG-MD.NET: When Brand Meets Peoplept_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/antiox8110563pt_PT
dc.identifier.issn2076-3921
dc.identifier.urihttp://hdl.handle.net/10400.1/13463
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAntioxidant capacitypt_PT
dc.subjectCeratonia siliqua Lpt_PT
dc.subjectEnzyme inhibitionpt_PT
dc.subjectGallic acidpt_PT
dc.subjectGastrointestinal digestionpt_PT
dc.subjectTotal phenolic contentpt_PT
dc.subjectDieta mediterrânica
dc.titleThe influence of in vitro gastrointestinal digestion on the chemical composition and antioxidant and enzyme inhibitory capacities of carob liqueurs obtained with different elaboration techniquespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue11pt_PT
oaire.citation.startPage563pt_PT
oaire.citation.titleAntioxidantspt_PT
oaire.citation.volume8pt_PT
person.familyNameRodríguez Solana
person.familyNameCoelho
person.familyNameGonçalves
person.familyNameRomano
person.givenNameRaquel
person.givenNameNatacha
person.givenNameSandra
person.givenNameAnabela
person.identifier624004
person.identifier.ciencia-idFE10-7889-0562
person.identifier.ciencia-idC518-BDB3-E127
person.identifier.ciencia-id9F19-E3AE-2C59
person.identifier.ciencia-id8A18-7E9A-3B0E
person.identifier.orcid0000-0003-4204-7387
person.identifier.orcid0000-0003-4265-5622
person.identifier.orcid0000-0002-3038-4434
person.identifier.orcid0000-0002-7204-7428
person.identifier.ridI-6317-2015
person.identifier.ridM-6988-2017
person.identifier.scopus-author-id55081917100
person.identifier.scopus-author-id8583003200
person.identifier.scopus-author-id56249997600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione54528cf-d25d-424e-b395-5f41019f05ee
relation.isAuthorOfPublication43b2d7ec-049a-412b-ad22-c9db64cc572c
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relation.isAuthorOfPublication.latestForDiscovery43b2d7ec-049a-412b-ad22-c9db64cc572c

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