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Publication
Nitração de tirosinas na miosina: consequências funcionais
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Advisor(s)
Abstract(s)
Tem sido demonstrado que o biomarcador 3-nitrotirosina (3-NT), frequentemente utilizado na reactividade do peroxinitrito (ONOO-) com as proteínas, aumenta na miosina após fibrilação atrial [Mihm et al, 2001b, 2003; Kooy et al, 1997] e durante o envelhecimento [Kansky et al, 2005a, 2005b; Hong et al, 2007].
The frequently used 3-nitrotyrosine (3-NT) biomarker of peroxynitrite (ONOO-)-reactivity to proteins has been shown to increase on myosin after atrial fibrillation [Mihm et al, 2001b, 2003; Kooy et al, 1997] and during aging [Kansky et al, 2005a, 2005b; Hong et al, 2007].
The frequently used 3-nitrotyrosine (3-NT) biomarker of peroxynitrite (ONOO-)-reactivity to proteins has been shown to increase on myosin after atrial fibrillation [Mihm et al, 2001b, 2003; Kooy et al, 1997] and during aging [Kansky et al, 2005a, 2005b; Hong et al, 2007].
Description
Relatório de estágio de licenciatura, Bioquímica, Faculdade de Ciências e Tecnologias da Universidade do Algarve, 2000
Keywords
Miosina Nitração Stress nitrosativo