Reactions of azovinylphosphonates with nucleophilic alkenes and heterocycles: synthesis of Tetrahydropyridazine-3-phosphonate and 2-Substituted-1-hydrazonoethylphosphonate derivatives

Lemos, A.; Lopes, Marta

http://hdl.handle.net/10400.1/5690

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
Phos sulfur 2008.pdf		197.48 KB	Adobe PDF	Download

Send Feedback

Authors

Lemos, A.

Lopes, Marta

Abstract(s)

Transient azovinylphosphonates, generated in situ by base induced dehydrohalogenation of the corresponding 2-bromo- and 2-chloro-acetylphosphonate- tertbutoxycarbonyl hydrazones are intercepted by electron rich alkenes and heterocycles in hetero Diels-Alder reactions, producing tetrahydopyridazine-3-phosphonates or open chain α-hydrazono phosphonates.

Keywords

α-hydrazonophosphonates 3-phosphono-1,2-diaza-1,3-butadienes Azovinylphosphonates Addition-elimination Cycloaddition Tetrahydropyridazine-3-phosphonates