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Toxicokinetics and tissue distribution of cadmium-based Quantum Dots in the marine mussel Mytilus galloprovincialis

dc.contributor.authorLopes Rocha, Thiago
dc.contributor.authorGomes, Tânia
dc.contributor.authorP. Pinheiro, José
dc.contributor.authorSerrão Sousa, Vânia
dc.contributor.authorNunes, Luís
dc.contributor.authorRibau Teixeira, Margarida
dc.contributor.authorBebianno, Maria João
dc.date.accessioned2020-04-22T11:34:40Z
dc.date.available2020-04-22T11:34:40Z
dc.date.issued2015-09
dc.description.abstractEnvironmental health hazards of Quantum Dots (QDs) are of emergent concern, but limited data is available about their toxicokinetics (TK) and tissue distribution in marine bivalves. This study investigated the QDs behavior in seawater, their TK and tissue distribution in Mytilus galloprovincialis, in comparison with soluble Cd. Mussels were exposed to CdTe QDs and soluble Cd for 21 days at 10 μgCd L(-1) followed by a 50 days depuration. TK of QDs in mussels is related to the homo-aggregate uptake, surface charge, aggregation and precipitation as key factors. There were tissue- and time-dependent differences in the TK of both Cd forms, and soluble Cd is the most bioavailable form. Digestive gland is a preferential site for QDs storage and both Cd forms are not eliminated by mussels (t1/2>50 days). Results indicate that the TK model of CdTe QDs in marine mussels is distinct from their soluble counterparts.pt_PT
dc.description.sponsorshipScience Without Borders Program from the Brazilian National Council for Scientific and Technological Development (CNPq) 239524/2012-8pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doihttps://doi.org/10.1016/j.envpol.2015.05.008pt_PT
dc.identifier.issn0269-7491
dc.identifier.urihttp://hdl.handle.net/10400.1/13748
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0269749115002419?via%3Dihubpt_PT
dc.subjectAnimalspt_PT
dc.subjectCadmiumpt_PT
dc.subjectMytiluspt_PT
dc.subjectQuantum Dotspt_PT
dc.subjectTissue distributionpt_PT
dc.subjectToxicokineticspt_PT
dc.subjectNanoparticlespt_PT
dc.subjectNanotoxicologypt_PT
dc.subjectBioaccumulationpt_PT
dc.subjectBivalvept_PT
dc.titleToxicokinetics and tissue distribution of cadmium-based Quantum Dots in the marine mussel Mytilus galloprovincialispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/COMPETE/PTDC%2FAAC-AMB%2F121650%2F2010/PT
oaire.citation.endPage214pt_PT
oaire.citation.startPage207pt_PT
oaire.citation.titleEnvironmental Pollutionpt_PT
oaire.citation.volume204pt_PT
oaire.fundingStreamCOMPETE
person.familyNameLopes Rocha
person.familyNameGomes
person.familyNamePinheiro
person.familyNameSerrão Sousa
person.familyNameNunes
person.familyNameRibau Teixeira
person.familyNameBebianno
person.givenNameThiago
person.givenNameTânia
person.givenNameJosé Paulo
person.givenNameVânia
person.givenNameLuís
person.givenNameMargarida
person.givenNameMaria
person.identifier93800
person.identifier.ciencia-id3D18-B03F-52FB
person.identifier.ciencia-id3112-1FCD-6685
person.identifier.ciencia-id9111-87FB-26AA
person.identifier.ciencia-id2B11-46AC-B94B
person.identifier.orcid0000-0003-0551-6842
person.identifier.orcid0000-0001-6179-4543
person.identifier.orcid0000-0001-7925-9733
person.identifier.orcid0000-0002-3800-1688
person.identifier.orcid0000-0001-5606-970X
person.identifier.orcid0000-0002-2153-3282
person.identifier.orcid0000-0003-1492-8566
person.identifier.ridA-3864-2015
person.identifier.ridE-8402-2013
person.identifier.ridM-4647-2013
person.identifier.ridB-9012-2012
person.identifier.scopus-author-id37007842200
person.identifier.scopus-author-id35838299700
person.identifier.scopus-author-id7102529511
person.identifier.scopus-author-id8988625600
person.identifier.scopus-author-id7004152715
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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