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The use of enhanced green fluorescent protein to track matrix Gla protein expression during zebrafish (Danio rerio) development

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dc.contributor.authorCardeira Da Silva, João
dc.contributor.authorGavaia, Paulo J.
dc.contributor.authorBrito, A. B.
dc.contributor.authorCancela, Leonor
dc.date.accessioned2014-06-18T08:53:58Z
dc.date.available2014-06-18T08:53:58Z
dc.date.issued2008
dc.description.abstractMatrix Gla protein (mgp), a vitamin K-dependent protein, is an important element of skeleton development as it regulates mineralization of both cartilaginous and bony structures, among others. Although mgp is found in a wide range of tissues, it is known to be expressed mostly by chondrocytes and vascular smooth muscle cells. Accordingly, inhibition of Mgp function results in over-mineralization of cartilages and growth plates and in ectopic mineralizations, particularly in the vascular system. Besides being a well characterized protein and the existence of developmental studies in zebrafish, there is still no description of monitoring mgp expression in live specimens.por
dc.description.sponsorshipThis work was partially funded by CCMARlplurianual funding. A.B. Brito is the recipient of a PhD fellowship from FCT.
dc.identifier.citationCardeira da Silva J., Gavaia P.J., Brito A.B., Cancela M.L. 2008. The use of enhanced green fluorescent protein to track matrix Gla protein expression during zebrafish (Danio rerio) development. Marine Genomics Europe final meeting. CCMAR-University of Algarve May 13-16, Faro, Portugal.por
dc.identifier.otherAUT: LCA00739
dc.identifier.urihttp://hdl.handle.net/10400.1/4353
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherMarine Genomics Europepor
dc.titleThe use of enhanced green fluorescent protein to track matrix Gla protein expression during zebrafish (Danio rerio) developmentpor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceFaropor
oaire.citation.titleMarine Genomics Europe final meetingpor
person.familyNameCardeira da Silva
person.familyNameGavaia
person.familyNameCancela
person.givenNameJoão
person.givenNamePaulo
person.givenNameM. Leonor
person.identifier.ciencia-idDC15-86F7-3AAC
person.identifier.ciencia-idB619-FC16-D007
person.identifier.orcid0000-0003-3722-8810
person.identifier.orcid0000-0002-9582-1957
person.identifier.orcid0000-0003-3114-6662
person.identifier.ridA-6470-2011
person.identifier.scopus-author-id55224020100
person.identifier.scopus-author-id6507104377
rcaap.rightsrestrictedAccesspor
rcaap.typeconferenceObjectpor
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relation.isAuthorOfPublication.latestForDiscovery9dca2139-21a4-4d59-aaf7-531f1033a58e

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