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Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection

dc.contributor.authorCurate, Francisco
dc.contributor.authorPerinha, Andreia
dc.contributor.authorSilva, Ana Maria
dc.contributor.authorCunha, Eugenia
dc.contributor.authorUmbelino, Cláudia
dc.contributor.authorNogueira, Catarina
dc.date.accessioned2020-07-24T10:53:23Z
dc.date.available2020-07-24T10:53:23Z
dc.date.issued2019-01
dc.description.abstractThere has been considerable progress in recent years in our understanding of the patterns of cortical bone loss in the second metacarpal in archeological skeletal samples. Nevertheless, cortical data from reference skeletal collections are insufficient, and the possible connection of metacarpal cortical parameters with osteoporotic fractures has not been thoroughly addressed. As such, this article aims to identify and explain sex-specific and age-associated metacarpal cortical bone loss in a large sample (N = 302
dc.description.abstractfemales: 154/males: 148) from the Coimbra Identified Skeletal Collection. Another objective is to evaluate the association of cortical and demographic features with osteoporotic fractures. Age-related endocortical bone loss is significant in women but not evident in men. Periosteal accretion of the bone is absent in both sexes. Overall, there is a net loss of the cortical bone in women, whereas cortical bone strength seems to be preserved in men. The prevalence of osteoporotic fractures is similar in both sexes, with age at death significantly influencing the probability of exhibiting a fracture. Metacarpal cortical index does not seem to be an independent risk factor for osteoporotic fractures in this sample.
dc.description.sponsorshipFundacao para a Ciencia e a TecnologiaPortuguese Foundation for Science and Technology [SFRH/BPD/74015/2010]
dc.identifier.doi10.1002/oa.2717
dc.identifier.issn1047-482X
dc.identifier.issn1099-1212
dc.identifier.urihttp://hdl.handle.net/10400.1/14485
dc.language.isoeng
dc.peerreviewedyes
dc.publisherWiley
dc.subjectX-ray radiogrammetry
dc.subjectMajor gene-control
dc.subjectHip-fractures
dc.subjectCompression fractures
dc.subjectAge
dc.subjectWomen
dc.subjectEpidemiology
dc.subjectMenopause
dc.subjectGeometry
dc.subjectIndex
dc.titleMetacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage81
oaire.citation.issue1
oaire.citation.startPage73
oaire.citation.titleInternational Journal of Osteoarchaeology
oaire.citation.volume29
person.familyNameUmbelino
person.givenNameCláudia
person.identifier.ciencia-id5710-349E-8BEE
person.identifier.orcid0000-0003-4834-7364
person.identifier.ridM-2783-2013
person.identifier.scopus-author-id7801372595
rcaap.rightsopenAccess
rcaap.typearticle
relation.isAuthorOfPublicatione077a563-3a7d-4a7a-b565-e49600d3d46d
relation.isAuthorOfPublication.latestForDiscoverye077a563-3a7d-4a7a-b565-e49600d3d46d

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