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Antioxidant and a-amylase inhibition activities of six plants used in the management of diabetes in Morocco

2024-03-30Artigo científico Acesso aberto
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datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg02:Erradicar a Fome
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorAazza, Smail
dc.contributor.authorEl-Guendouz, Soukaina
dc.contributor.authorMiguel, Maria da Graça
dc.date.accessioned2026-05-22T15:33:57Z
dc.date.available2026-05-22T15:33:57Z
dc.date.issued2024-03-30
dc.description.abstractDiabetes mellitus is one of the major health problems in the world. Conventional antidiabetic drugs are effective; however, they also with unavoidable side effects. On the other hand, plants may be an alternative source of antidiabetic agents. In the present study, six plants (Cynara scolymus, Ceratonia siliqua, Centaurium erythraea, Marrubium vulgare, Salvia officinalis, and Ziziphus lotus reputed for their antidiabetic effect in Moroccan traditional medicine were chosen. The work was focused on the determination of the antioxidant activities by several methods, including as well as their -amylase inhibitory capacity. It was noted that S. officinalis extract contained the highest phenolic contents and the strongest ABTS and nitric oxide scavenging activities. C. erythraea has the highest total flavonoid content and the best total antioxidant activity. M. vulgare showed the best -amylase inhibitory activity and the best chelating power abreast with C. scolymus, which presented very weak antioxidant activities unless good -amylase inhibition. Principal component analysis (PCA) showed a very good correlation between total phenolic content and 2,2-diphenyl-1-picrylhydrazyl (DPPH) along with 2,2'-azino-bis(3- ethylbenzothiazoline-6-sulfonic acid) (ABTS) free radicals scavenging activities. M. vulgare displayed the best α-amylase inhibition capacity.eng
dc.identifier.doi10.33263/lianbs131.017
dc.identifier.issn2284-6808
dc.identifier.urihttp://hdl.handle.net/10400.1/29023
dc.language.isoeng
dc.peerreviewedyes
dc.publisherAMG Transcend Association
dc.relationMediterranean Institute for Agriculture, Environment and Development
dc.relation.ispartofLetters in Applied NanoBioScience
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCynara scolymus
dc.subjectCeratonia siliqua
dc.subjectCentaurium erythraea
dc.subjectMarrubium vulgare
dc.subjectSalvia officinalis
dc.subjectZiziphus lotus
dc.titleAntioxidant and a-amylase inhibition activities of six plants used in the management of diabetes in Moroccoeng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/05183/2020
oaire.awardTitleMediterranean Institute for Agriculture, Environment and Development
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F05183%2F2020/PT
oaire.citation.endPage26
oaire.citation.issue1
oaire.citation.startPage1
oaire.citation.titleLetters in Applied NanoBioScience
oaire.citation.volume13
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameMiguel
person.givenNameMaria da Graça
person.identifier.ciencia-id6110-6FE7-DF28
person.identifier.orcid0000-0003-2507-4228
person.identifier.scopus-author-id35562054500
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublication2507350f-9e60-4d4a-a096-53e58d93549c
relation.isAuthorOfPublication.latestForDiscovery2507350f-9e60-4d4a-a096-53e58d93549c
relation.isProjectOfPublication823bd652-ee6c-4479-91c5-06095bc37e9c
relation.isProjectOfPublication.latestForDiscovery823bd652-ee6c-4479-91c5-06095bc37e9c

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