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Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal

dc.contributor.authorMiguel, Maria
dc.contributor.authorGago, Custódia
dc.contributor.authorAntunes, Maria Dulce
dc.contributor.authorMegias, Cristina
dc.contributor.authorCortes-Giraldo, Isabel
dc.contributor.authorVioque, Javier
dc.contributor.authorSofia Lima, A.
dc.contributor.authorCristina Figueiredo, A.
dc.date.accessioned2018-12-07T14:58:26Z
dc.date.available2018-12-07T14:58:26Z
dc.date.issued2015
dc.description.abstractThe antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, alpha-terpineol, and gamma-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(center dot+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
dc.description.sponsorshipFundacao para a Ciencia e Tecnologia (FCT) [Pest-OE/EQB/LA0023/2011]
dc.identifier.doi10.1155/2015/851721
dc.identifier.issn1741-427X
dc.identifier.issn1741-4288
dc.identifier.urihttp://hdl.handle.net/10400.1/12022
dc.language.isoeng
dc.peerreviewedyes
dc.publisherHindawi Publishing Corporation
dc.subjectAssay
dc.titleAntioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAMB%2F50017%2F2013/PT
oaire.citation.startPage851721
oaire.citation.titleEvidence-Based Complementary and Alternative Medicine
oaire.fundingStream5876
person.familyNameMiguel
person.familyNameGago
person.familyNameAntunes
person.givenNameMaria da Graça
person.givenNameCustódia
person.givenNameMaria Dulce
person.identifier177556
person.identifier.ciencia-id6110-6FE7-DF28
person.identifier.ciencia-id6517-A4D9-05AD
person.identifier.ciencia-idC11B-9B05-217E
person.identifier.orcid0000-0003-2507-4228
person.identifier.orcid0000-0001-9914-3615
person.identifier.orcid0000-0002-8913-6136
person.identifier.ridG-8496-2019
person.identifier.ridA-4683-2012
person.identifier.scopus-author-id35562054500
person.identifier.scopus-author-id37060829600
person.identifier.scopus-author-id7102645075
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccess
rcaap.typearticle
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