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Advisor(s)
Abstract(s)
Taurine is a sulphur-containing amino acid with important physiological roles and a key
compound for the synthesis of bile salts, which are essential for the emulsion and absorption of
dietary lipids. This study aimed to evaluate the effects of taurine supplementation to low-fishmeal
diets on the metabolism of taurine, bile acids, and lipids of Senegalese sole. A fishmeal (FM) and
a plant-protein-based (PP0) diet were formulated, and the latter was supplemented with taurine
at 0.5 and 1.5% (diets PP0.5 and PP1.5). Diets were assigned to triplicate tanks containing 35 fish
(initial weight ~14 g) for 6 weeks. Fish from the PP0 treatment presented lower taurine and bile-acid
concentrations compared with the FM treatment, and a downregulation of cyp7a1 and abcb11 was
observed. Triolein catabolism decreased in PP0-fed fish, resulting in increased hepatic fat content and
plasma triglycerides, while no effects on plasma cholesterol were observed. Taurine supplementation
to plant-based diets resulted in a higher taurine accumulation in fish tissues, increased bile-acid
concentration, and upregulation of cyp7a1 and abcb11. Hepatic fat content and plasma triglycerides
decreased with increasing dietary taurine supplementation. Taurine supplementation mitigated part
of the negative effects of plant-based diets, leading to better lipid utilisation.
Description
Keywords
Aquaculture Solea senegalensis Flatfish Fishmeal replacement Taurine Bile acids Lipid utilisation Metabolic trials
Citation
Animals 13 (9): 1501 (2023)
Publisher
MDPI