Repository logo
 
Publication

Putative role of flavobacterium, dokdonella and methylophilus strains in paracetamol biodegradation

2018Journal article Open access
Simple item page
dc.contributor.authorDa Luz Palma, Tânia Cristina
dc.contributor.authorMbagag NEBA, Donaldben
dc.contributor.authorCosta, Maria Clara
dc.contributor.authorCarlier, Jorge
dc.date.accessioned2020-08-05T13:13:15Z
dc.date.available2020-08-05T13:13:15Z
dc.date.issued2018
dc.description.abstractParacetamol, the most widely and globally used analgesic and antipyretic, is easily accumulated in aquatic environments. In the present study, the biodegradation of paracetamol in different media (one for general growth, one specific for sulfate reducing bacteria, a mineral salts medium and municipal wastewater) inoculated with two types of sludge (from anaerobic lagoon and from oxidation ditch) under different oxygenic conditions (anoxic; moderate oxygenation in open flasks and high oxygenation by aeration) was investigated. In addition, bacteria with relative abundances increasing simultaneously with paracetamol degradation, when this drug was the only carbon source, thus with a putative role in its degradation, were identified using 16S rRNA gene sequences. The results show that aerobic microorganisms had a major role in the degradation of paracetamol, with 50 mg/L totally removed from municipal wastewater after 2 days incubation with aeration, and that the metabolites 4-aminophenol and hydroquinone plus one compound not identified in this work were produced in the process. The identification of bacteria with a role in the degradation of paracetamol revealed a strain from genus Pseudomonas with the highest final relative abundance of 21.2%, confirming previous works reporting strains of this genus as paracetamol decomposers. Besides, genera Flavobacterium, Dokdonella and Methylophilus were also in evidence, with initial relative abundances of 1.66%, 1.48 and 0.00% (not detected) in the inoculum and 6.91%, 3.80 and 3.83% after incubation, respectively. Therefore, a putative role of these genera in paracetamol biodegradation is suggested for the first time.pt_PT
dc.description.sponsorshipErasmus Mundus Master in Chemical Innovation and Regulations (EMMC-ChIR) of Donaldben Mbagag NEBA by the Erasmus Mundus program of the European Commissionpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1007/s11270-018-3858-2pt_PT
dc.identifier.issn0049-6979
dc.identifier.urihttp://hdl.handle.net/10400.1/14605
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.relationBiodegradation of widely used pharmaceutical compounds by bacterial communities
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAcetaminophenpt_PT
dc.subject4-Aminophenolpt_PT
dc.subjectBioremediationpt_PT
dc.subjectHydroquinonept_PT
dc.subjectPharmaceutical compoundspt_PT
dc.titlePutative role of flavobacterium, dokdonella and methylophilus strains in paracetamol biodegradationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleBiodegradation of widely used pharmaceutical compounds by bacterial communities
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F95075%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04326%2F2013/PT
oaire.citation.issue6pt_PT
oaire.citation.startPage200pt_PT
oaire.citation.titleWater, Air, and Soil Pollutionpt_PT
oaire.citation.volume229pt_PT
oaire.fundingStream5876
person.familyNameDa Luz Palma
person.familyNameMbagag NEBA
person.familyNameCosta
person.familyNameCarlier
person.givenNameTânia Cristina
person.givenNameDonaldben
person.givenNameMaria Clara
person.givenNameJorge
person.identifier.ciencia-id0614-DE1E-9632
person.identifier.ciencia-id7110-A28E-3C8A
person.identifier.ciencia-id691D-A1BB-15CC
person.identifier.orcid0000-0001-8614-570X
person.identifier.orcid0000-0002-0078-340X
person.identifier.orcid0000-0003-1340-5237
person.identifier.orcid0000-0003-0675-2716
person.identifier.ridM-6189-2013
person.identifier.scopus-author-id35354952400
person.identifier.scopus-author-id7102166949
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication14822b7f-c0d1-4fd1-9942-b9487903603a
relation.isAuthorOfPublication2b736c74-7753-47a7-9f2f-8f3a1cabf2f5
relation.isAuthorOfPublication11c29f10-6e2b-40d8-9c74-2cc45be6d7a7
relation.isAuthorOfPublicationd4af2b00-61d6-4fd9-b05d-9ed235b5c7de
relation.isAuthorOfPublication.latestForDiscovery11c29f10-6e2b-40d8-9c74-2cc45be6d7a7
relation.isProjectOfPublicationc3ca4a85-a07e-4b48-934e-04c63a8d268f
relation.isProjectOfPublication868b4818-3efa-4edb-9202-c464d64fd38f
relation.isProjectOfPublication.latestForDiscovery868b4818-3efa-4edb-9202-c464d64fd38f

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Jorge Carlier - Palma-et-al-2018-ressubmission.pdf
Size:
4.3 MB
Format:
Adobe Portable Document Format
Download

Collections

CCM2-Artigos (em revistas ou actas indexadas)
FCT2-Artigos (em revistas ou actas indexadas)