ULS_10.2-MED-Conferências
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- 313P Disease and treatment patterns for advanced cholangiocarcinoma: A multicentric study from PortugalPublication . Gonçalves, J. C. N.; Freitas, A. R. R.; Fortuna, A. R.; Menezes, M. B.; Gramaça, J.; Fernandes, I. C. Gomes; Ângelo, I. C.; Trabulo, C. F. P.; Sousa, C. Xavier de; Pina, I. M. MatosGemcitabine plus cisplatin (GC) was standard first-line treatment for advanced biliary tract cancers until recently, supported by the UK ABC-02 study. However, TOPAZ-1 showed survival improvement with Durvalumab plus GC. Nevertheless, a significant proportion of patients face challenges with GC tolerability, prompting into alternatives such as gemcitabine and carboplatin (GCb). Moreover, there remains a paucity of stratified data pertaining to cholangiocarcinomas (CCA). We analyzed 5-year trends to determine treatment rates and cisplatin use in the real world.
- Adalimumab and number of previous biological disease-modifying antirheumatic drugs as predictive factors for the development of immune-mediated skin lesionsPublication . Martins, A.; Oliveira, D. Santos; Martins, F. R.; Nicolau, R.; Pinheiro, F. Oliveira; Rato, M.; Bernardo, A.; Pimenta, S.; Bernardes, M.; Costa, L.Treatment of inflammatory rheumatic diseases has dramatically changed with the introduction of biologic disease modifying anti-rheumatic drugs (bDMARDs). However, these drugs aren’t exempt from risks and skin lesions are the most frequent adverse reactions. Among the possible adverse skin reactions, immune-mediated skin lesions (IMSL) may occur. Risk factors associated with the occurrence of IMSL in rheumatic patients under bDMARDs are poorly known and studied.
- Asdas responses in patients with axial Spondyloarthritis starting bdmards: results from a multicentre prospective cohortPublication . Santos, M. E.; Ramiro, S.; van der Heijde, D.; Landewe, R.ASAS and EULAR recommend the use of an improvement ≥1.1 in ASDAS at 12 weeks to determine the continuation of a bDMARD. However, it is debated whether improvements can occur and whether patients’ characteristics influence (time to) response.
- Asdas responses in patients with axial spondyloarthritis starting bdmards: results from a multicentre prospective cohortPublication . Santos, M. E.; Ramiro, S.; Van der Heijde, D.; Landewé, R.; Santos, F. Pimentel; Machado, A. R. Cruz; Ferreira, C.; Gomes, C.; Soares, C. Dantas; Miguel, C.; Albuquerque, F.; Martins, F.; Silva, L.; Santos, H.; Almeida, I.; Bernardes, M.; Khmelinskii, N.; Valente, P.; Teixeira, P. M.; Matias, S. Emídio; Fraga, V.; Branco, J. C.; Sepriano, A.ASAS and EULAR recommend the use of an improvement ≥1.1 in ASDAS at 12 weeks to determine the continuation of a bDMARD. However, it is debated whether improvements can occur and whether patients’ characteristics influence (time to) response.
- Calcium/magnesium ratio in patients with diabetes and chronic kidney disease: a risk factor for cardiovascular diseasePublication . Borges, Henrique; Afonso, Rita; Marques, Roberto Calças; Jerónimo, Teresa; Silva, AnaChronic Kidney Disease (CKD) and Diabetes Mellitus (DM) are significant risk factors for Cardiovascular (CV) Disease. Patients with CKD and/or DM exhibit higher incidence and prevalence of CV events compared to the general population. Hypomagnesemia and elevated calcium-magnesium (Ca:Mg) ratios have been identified as independent risk factors for CV-related deaths. The aim of this study is to determine the relationship between Ca:Mg and the prognosis of CV disease in patients with CKD and DM.
- Characterization of Clostridioides strains and antibiotic resistance profile in Inflammatory Bowel Disease patients with Clostridioides infectionPublication . Oliveira, R.; Sousa, H. Tavares de; Roseira, J.There is an increasing incidence of community-acquired Clostridioides difficile infection (CDI), particularly in IBD. Due to a suspected community outbreak in mid-2023, we aimed to investigate the microbiological and antibiotic resistance profile of CDI in an IBD cohort, employing blind central reading, in order to better understand its epidemiology.
- Chlamydia trachomatis and Neisseria gonorrhoeae detection: Comparing the recommended detection methods and the ones used in a regional hospital laboratoryPublication . Ling, T.; Pereira, A.; Loureiro, A.; Silva, M. J.Sexually Transmitted Infections (STI) are a group of infections that spread primarily through unprotected sexual contact and can cause serious consequences if not treated. STIs continue to be a significant public health issue with a direct impact in the sexual health of millions of people worldwide.
- Chlamydia trachomatis and Neisseria gonorrhoeae detection: Comparing the recommended detection methods and the ones used in a regional hospital laboratoryPublication . Ling, T.; Pereira, A.; Loureiro, A.; Silva, M. J.Sexually Transmitted Infections (STI) are a group of infections that spread primarily through unprotected sexual contact and can cause serious consequences if not treated. STIs continue to be a significant public health issue with a direct impact in the sexual health of millions of people worldwide.
- Clinical characteristics and outcomes of PTLD after kidney transplant: a single center experiencePublication . Afonso, Rita; Nicolau, Carla; Vieira, Miguel Bigotte; Caeiro, Fernando; Jorge, CristinaPost-Transplant Lymphoproliferative Disorder (PTLD) is a serious and potentially fatal complication of immunosuppression in kidney transplantation. Given the rarity of this entity, a high index of suspicion is necessary. We aimed to review the incidence, clinical presentation, histological subtypes, treatment, patient and graft survival of PTLD in kidney transplant patients in our unit.
- Clinical profile and treatment outcomes in patients receiving advanced therapies for ulcerative colitis – the READ-UC real-world studyPublication . Fernandes, S. R.; Sousa, H. Tavares de; Portela, F.; Ministro, P.; Lago, P.; Branquinho, D.; Freitas, I.; Machado, N. Martins; Magro, F.Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that requires effective treatment with the main goal of inducing and maintaining remission. This study aimed to characterize UC patients receiving advanced therapies (AT), by describing their demographic and clinical characteristics and remission outcomes.