ULS_10.2-MED-Conferências
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- 313P Disease and treatment patterns for advanced cholangiocarcinoma: A multicentric study from PortugalPublication . Gonçalves, J. C. N.; Freitas, A. R. R.; Fortuna, A. R.; Menezes, M. B.; Gramaça, J.; Fernandes, I. C. Gomes; Ângelo, I. C.; Trabulo, C. F. P.; Sousa, C. Xavier de; Pina, I. M. MatosGemcitabine plus cisplatin (GC) was standard first-line treatment for advanced biliary tract cancers until recently, supported by the UK ABC-02 study. However, TOPAZ-1 showed survival improvement with Durvalumab plus GC. Nevertheless, a significant proportion of patients face challenges with GC tolerability, prompting into alternatives such as gemcitabine and carboplatin (GCb). Moreover, there remains a paucity of stratified data pertaining to cholangiocarcinomas (CCA). We analyzed 5-year trends to determine treatment rates and cisplatin use in the real world.
- Asdas responses in patients with axial Spondyloarthritis starting bdmards: results from a multicentre prospective cohortPublication . Santos, M. E.; Ramiro, S.; van der Heijde, D.; Landewe, R.ASAS and EULAR recommend the use of an improvement ≥1.1 in ASDAS at 12 weeks to determine the continuation of a bDMARD. However, it is debated whether improvements can occur and whether patients’ characteristics influence (time to) response.
- Asdas responses in patients with axial spondyloarthritis starting bdmards: results from a multicentre prospective cohortPublication . Santos, M. E.; Ramiro, S.; Van der Heijde, D.; Landewé, R.; Santos, F. Pimentel; Machado, A. R. Cruz; Ferreira, C.; Gomes, C.; Soares, C. Dantas; Miguel, C.; Albuquerque, F.; Martins, F.; Silva, L.; Santos, H.; Almeida, I.; Bernardes, M.; Khmelinskii, N.; Valente, P.; Teixeira, P. M.; Matias, S. Emídio; Fraga, V.; Branco, J. C.; Sepriano, A.ASAS and EULAR recommend the use of an improvement ≥1.1 in ASDAS at 12 weeks to determine the continuation of a bDMARD. However, it is debated whether improvements can occur and whether patients’ characteristics influence (time to) response.
- Characterization of Clostridioides strains and antibiotic resistance profile in Inflammatory Bowel Disease patients with Clostridioides infectionPublication . Oliveira, R.; Sousa, H. Tavares de; Roseira, J.There is an increasing incidence of community-acquired Clostridioides difficile infection (CDI), particularly in IBD. Due to a suspected community outbreak in mid-2023, we aimed to investigate the microbiological and antibiotic resistance profile of CDI in an IBD cohort, employing blind central reading, in order to better understand its epidemiology.
- Chlamydia trachomatis and Neisseria gonorrhoeae detection: Comparing the recommended detection methods and the ones used in a regional hospital laboratoryPublication . Ling, T.; Pereira, A.; Loureiro, A.; Silva, M. J.Sexually Transmitted Infections (STI) are a group of infections that spread primarily through unprotected sexual contact and can cause serious consequences if not treated. STIs continue to be a significant public health issue with a direct impact in the sexual health of millions of people worldwide.
- Chlamydia trachomatis and Neisseria gonorrhoeae detection: Comparing the recommended detection methods and the ones used in a regional hospital laboratoryPublication . Ling, T.; Pereira, A.; Loureiro, A.; Silva, M. J.Sexually Transmitted Infections (STI) are a group of infections that spread primarily through unprotected sexual contact and can cause serious consequences if not treated. STIs continue to be a significant public health issue with a direct impact in the sexual health of millions of people worldwide.
- Clinical characteristics and outcomes of PTLD after kidney transplant: a single center experiencePublication . Afonso, Rita; Nicolau, Carla; Vieira, Miguel Bigotte; Caeiro, Fernando; Jorge, CristinaPost-Transplant Lymphoproliferative Disorder (PTLD) is a serious and potentially fatal complication of immunosuppression in kidney transplantation. Given the rarity of this entity, a high index of suspicion is necessary. We aimed to review the incidence, clinical presentation, histological subtypes, treatment, patient and graft survival of PTLD in kidney transplant patients in our unit.
- Enhancing primary prevention: the incremental predictive value of high-sensitivity cardiac troponin T beyond ASCVD risk assessmentPublication . Andraz, S.; Pereira, J. Massa; Costa, H.; Espirito Santo, M.; Hamann, L.; Fernandes, R.; Bispo, J.; Carvalho, D.; Bento, D.; Azevedo, P.; Mimoso, J.Atherosclerotic cardiovascular disease (ASCVD) is a global health challenge, prompting widespread use of conventional risk assessment tools (SCORE2 in Europe and the ASCVD Risk calculator in the United States) to guide preventive strategies. Emerging evidence indicates that high-sensitivity cardiac troponin (hsTn) may refine risk stratification.
- Hemolytic uremic syndrome in children: a case reportPublication . Ling, T.; Loureiro, A.; Silva, M. J.The Hemolytic Uremic Syndrome (HUS) is characterized by the simultaneous occurrence of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury, caused by microvascular thrombosis. HUS can be classified as acquired or hereditary according to its pathophysiology. The main cause of acquired HUS are infections caused by Shiga toxin-producing Escherichia coli infections (STEC-HUS), while hereditary HUS is mainly caused by complement factors gene mutations. Worldwide incidence of HUS is estimated to be 2-3 cases per 100.000 children, of which 90% are STEC-HUS.
- Minimally invasive treatment of gastric GIST by endo-laparoscopyPublication . Cunha, Miguel; Hristrova, K.; Roseira, Joana; Hugo, V.; Melo, J.; Veiga, D.; Peixe, B.; Sousa, Helena Tavares; Rachadell, J.; Amorim, E.; Americano, M.The gastrointestinal stromal tumor,s (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract. Surgery is the primary therapeutic approach. Objective: To present the results of patients undergoing combined endo-laparoscopic (ELC) approach as a minimally invasive treatment for gastric GISTs