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Chemical composition and biological screening of the essential oils of Micromeria macrosiphon and M. arganietorum (Lamiaceae)

2021Journal article Restricted access
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dc.contributor.authorEl Yaagoubi, Mohamed
dc.contributor.authorMechqoq, Hicham
dc.contributor.authorOrtiz, Sergio
dc.contributor.authorCavaleiro, Carlos
dc.contributor.authorLecsö‐Bornet, Marylin
dc.contributor.authorPereira, Catarina
dc.contributor.authorRodrigues, Maria Joao
dc.contributor.authorCustódio, Luísa
dc.contributor.authorEl Mousadik, Abdelhamid
dc.contributor.authorPicot, Laurent
dc.contributor.authorKritsanida, Marina
dc.contributor.authorMsanda, Fouad
dc.contributor.authorEl Aouad, Noureddine
dc.contributor.authorGrougnet, Raphaël
dc.date.accessioned2022-02-16T09:42:25Z
dc.date.available2022-02-16T09:42:25Z
dc.date.issued2021
dc.description.abstractThe chemical composition and in vitro biological activities of the essential oil (EO) of Micromeria macrosiphon Coss. and M. arganietorum (J. Emb.) R. Morales, two Lamiaceae endemic to south Morocco, were investigated. GC/MS analysis resulted in the identification of 36 metabolites from the EO of M. macrosiphon, 45 from M. arganietorum. Borneol was the major metabolite in both oils and together with related derivatives such as camphor, accounted for 2/3 of the EO of M. macrosiphon, 1/3 of those of M. arganietorum. Pinene and terpinene derivatives were also present in high proportions. From a chemotaxonomic point of view, the composition of the examined samples may be related to those of other species endemic to Macaronesia. Both EOs showed significant toxicity towards liver HepG2 and melanoma B16 4A5 tumor cell lines at 100 mu g/mL; however, they were also cytotoxic towards S17 normal cell lines, with a selectivity index <1. No antibacterial activity was noticed against 52 strains at 100 mu g/mL.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1002/cbdv.202100653pt_PT
dc.identifier.issn1612-187
dc.identifier.urihttp://hdl.handle.net/10400.1/17560
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relationExploitation of aromatic plants’ by-products for the development of novel cosmeceuticals and food supplements.
dc.relationAlgarve Centre for Marine Sciences
dc.relationChemical Process Engineering and Forest Products Research Centre
dc.relationNot Available
dc.subjectMicromeria macrosiphonpt_PT
dc.subjectEssential oilpt_PT
dc.subjectM arganietorumpt_PT
dc.subjectBiological activitiespt_PT
dc.subjectBorneolpt_PT
dc.titleChemical composition and biological screening of the essential oils of Micromeria macrosiphon and M. arganietorum (Lamiaceae)pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleExploitation of aromatic plants’ by-products for the development of novel cosmeceuticals and food supplements.
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleChemical Process Engineering and Forest Products Research Centre
oaire.awardTitleNot Available
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/691247/EU
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00102%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/CEEC IND 2017/CEECIND%2F00425%2F2017%2FCP1391%2FCT0001/PT
oaire.citation.issue12pt_PT
oaire.citation.startPagee202100653pt_PT
oaire.citation.titleChemistry & Biodiversitypt_PT
oaire.citation.volume18pt_PT
oaire.fundingStreamH2020
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamCEEC IND 2017
person.familyNameGuerreiro Pereira
person.familyNameRodrigues
person.familyNameCustódio
person.givenNameCatarina Alexandra
person.givenNameMaria João
person.givenNameLuísa
person.identifierNmxO5SIAAAAJ
person.identifierR-004-VNG
person.identifier.ciencia-id4512-3435-689C
person.identifier.ciencia-id2514-0E17-1D8D
person.identifier.ciencia-id791B-C560-AEA2
person.identifier.orcid0000-0002-1131-8773
person.identifier.orcid0000-0001-8732-710X
person.identifier.orcid0000-0003-4338-7703
person.identifier.ridM-6101-2013
person.identifier.scopus-author-id56031608100
person.identifier.scopus-author-id15831018900
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameEuropean Commission
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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