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Polén apícola: benefícios nutricionais e medicinais
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Abstract(s)
Historicamente os produtos apícolas foram utilizados como uma abordagem terapêutica e no consumo de alimentos, enquanto os dados mais recentes incluem alguns detalhes importantes que poderiam validá-los como suplementos alimentares e como medicamentos devido às suas propriedades biológicas. Neste trabalho de revisão, foram abordadas diversas pesquisas científicas sobre o pólen apícola (PA), onde foram estudadas e analisadas as suas propriedades nutricionais e medicinais, bem como as principais limitações da sua utilização. A ingestão de antioxidantes dietéticos derivados de PA está associada com a prevenção e tratamento de múltiplas doenças. Os efeitos benéficos do PA na saúde resultam da presença de múltiplos polifenóis que possuem propriedades anti-inflamatórias, fitoesteróis e ácidos gordos, que desempenham funções anticancerígenas, bem como polissacáridos, que estimulam a atividade imunológica. Dos principais estudos de atividade biológica do PA, in vitro e experiências com animais, a estimulação da apoptose e a inibição da proliferação celular em múltiplas linhas celulares podem ser um dos principais efeitos adjuvantes terapêuticos a serem explorados na redução do crescimento dos tumores nos humanos. A crescente investigação da atividade do PA na área de urologia e na área de imunoallergologia levara num futuro próximo a uma maior utilização do pólen apícola nos tratamentos contra a prostatite cronica nos homens e contra a febre dos fenos. Além disso, será apresentada uma discussão sobre as lacunas de investigação para ajudar a realizar novas experiências que completam as principais diretivas de eficiência, segurança e controlo de qualidade da Organização Mundial de Saúde (OMS) para estes produtos.
Historically, beehive products have been used as a therapeutic approach and in nutrition, while the latest data include some important details that could validate them as dietary supplements and as medication due to their biological properties. In this review, several scientific research on bee pollen (BP) was mentioned, where its nutritional and medicinal properties were studied and analyzed, as well as the main limitations of its use. The intake of dietary antioxidants derived from BP is associated with the prevention and treatment of multiple diseases. The beneficial health effects of BP result from the presence of multiple polyphenols, that have anti-inflammatory properties, phytosterol and fatty acids that perform anticancer functions, as well as polysaccharides, which stimulate immune activity. Of the main studies of biological activity of experiments in BP, in vitro and animals, the stimulation of apoptosis and inhibition of cell proliferation in multiple cell lines may be one of the main therapeutic adjuvant effects to be explored in reducing tumor growth in humans. The increasing investigation of BP activity in the area of urology and in the area of immunoallergology will lead, soon, to a greater use of bee pollen in treatments against chronic prostatitis in men and hay fever. In addition, a discussion regarding some important gaps in research will be presented to help carry out new experiments that complete the main World Health Organisation (WHO) efficiency, safety and quality control directives for these products.
Historically, beehive products have been used as a therapeutic approach and in nutrition, while the latest data include some important details that could validate them as dietary supplements and as medication due to their biological properties. In this review, several scientific research on bee pollen (BP) was mentioned, where its nutritional and medicinal properties were studied and analyzed, as well as the main limitations of its use. The intake of dietary antioxidants derived from BP is associated with the prevention and treatment of multiple diseases. The beneficial health effects of BP result from the presence of multiple polyphenols, that have anti-inflammatory properties, phytosterol and fatty acids that perform anticancer functions, as well as polysaccharides, which stimulate immune activity. Of the main studies of biological activity of experiments in BP, in vitro and animals, the stimulation of apoptosis and inhibition of cell proliferation in multiple cell lines may be one of the main therapeutic adjuvant effects to be explored in reducing tumor growth in humans. The increasing investigation of BP activity in the area of urology and in the area of immunoallergology will lead, soon, to a greater use of bee pollen in treatments against chronic prostatitis in men and hay fever. In addition, a discussion regarding some important gaps in research will be presented to help carry out new experiments that complete the main World Health Organisation (WHO) efficiency, safety and quality control directives for these products.
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Keywords
Pólen apícola Benefícios nutricionais Atividade biológica Aplicação terapêutica