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Abstract(s)
A indústria cosmética é um setor em crescimento, onde a procura por novos compostos
ativos para melhorar e criar produtos inovadores é bastante importante. As preferências do
consumidor evoluíram e surgiu uma consciência mais ecológica, pelo que, os consumidores
exigem mais produtos naturais, com menos implicações ambientais e menos efeitos tóxicos.
Nesse contexto, as macroalgas podem representar uma fonte rica em diferentes metabolitos,
com fácil acessibilidade para a obtenção dessas moléculas.
A radiação ultravioleta da luz solar é o principal fator ambiental que induz o
envelhecimento da pele humana e resulta na acumulação de pigmentos e na formação de rugas.
A pele humana é frequentemente afetada pelo stresse oxidativo causado pela exposição
contínua à radiação solar ultravioleta.
As macroalgas estão naturalmente expostas ao stress oxidativo, pelo que desenvolvem
compostos bioativos com capacidade antioxidante, sendo capazes de metabolizar os radicais
livres e consequentemente, neutralizar os efeitos nocivos induzidos pelo stresse oxidativo.
Desta forma, os compostos bioativos de macroalgas podem integrar formulações cosméticas
contra os efeitos nocivos da radiação ultravioleta, apresentando um efeito de anti envelhecimento.
A presente dissertação foca-se na procura de novos compostos com atividade
antioxidante obtidos a partir de organismos marinhos (particularmente macroalgas) com
potencial na indústria cosmética, através da análise de estudos realizados in vitro.
Concluiu-se que as macroalgas de um determinado filo, nomeadamente Phaeophyceae,
apresentam na sua composição química maior quantidade de compostos com atividade
antioxidante, possuindo uma elevada atividade antioxidante in vitro. Estas macroalgas devem
ser consideradas para futuros estudos in vivo e em formulações de produtos cosméticos
inovadores.
The cosmetic industry is a growing sector, where the search for new active compounds to improve and create innovative products is crucial. Consumer preferences have evolved and a greener awareness has emerged, whereby consumers demand more natural products, with fewer environmental implications and less toxic effects. In this context, macroalgae can represent a rich source of different metabolites with easy accessibility to obtain these molecules. Ultraviolet radiation from sunlight is the main environmental factor that induces the aging of human skin and results in the accumulation of pigments and the formation of wrinkles. Human skin is often affected by oxidative stress caused by continuous exposure to ultraviolet solar radiation. Macroalgae are naturally exposed to oxidative stress, so they develop bioactive compounds with antioxidant capacity, being able to metabolize free radicals and, consequently, neutralize the harmful effects induced by oxidative stress. In this way, macroalgal bioactive compounds can integrate cosmetic formulations against the harmful effects of ultraviolet radiation, presenting an anti-aging effect. This dissertation focuses on the search for new compounds with antioxidant activity obtained from marine organisms (particularly macroalgae) with potential in the cosmetic industry, through the analysis of in vitro studies. It was concluded that the macroalgae of a certain phylum, namely Phaeophyceae, present in their chemical composition a greater amount of compounds with antioxidant activity, having a high antioxidant activity in vitro. These macroalgae should be considered for future in vivo studies and in innovative cosmetic product formulation.
The cosmetic industry is a growing sector, where the search for new active compounds to improve and create innovative products is crucial. Consumer preferences have evolved and a greener awareness has emerged, whereby consumers demand more natural products, with fewer environmental implications and less toxic effects. In this context, macroalgae can represent a rich source of different metabolites with easy accessibility to obtain these molecules. Ultraviolet radiation from sunlight is the main environmental factor that induces the aging of human skin and results in the accumulation of pigments and the formation of wrinkles. Human skin is often affected by oxidative stress caused by continuous exposure to ultraviolet solar radiation. Macroalgae are naturally exposed to oxidative stress, so they develop bioactive compounds with antioxidant capacity, being able to metabolize free radicals and, consequently, neutralize the harmful effects induced by oxidative stress. In this way, macroalgal bioactive compounds can integrate cosmetic formulations against the harmful effects of ultraviolet radiation, presenting an anti-aging effect. This dissertation focuses on the search for new compounds with antioxidant activity obtained from marine organisms (particularly macroalgae) with potential in the cosmetic industry, through the analysis of in vitro studies. It was concluded that the macroalgae of a certain phylum, namely Phaeophyceae, present in their chemical composition a greater amount of compounds with antioxidant activity, having a high antioxidant activity in vitro. These macroalgae should be considered for future in vivo studies and in innovative cosmetic product formulation.
Description
Keywords
Antioxidante Compostos bioativos Phaeophyceae Chlorophyta Rodophyta