Publication
Establishment of an induced pluripotent cell line (ABCRIi001-A) from an elderly female for ageing research
dc.contributor.author | Esteves, Filipa | |
dc.contributor.author | Vilhena Catarino Brito, David | |
dc.contributor.author | Rajado, Ana Teresa | |
dc.contributor.author | Silva, NĂĄdia | |
dc.contributor.author | ApolĂłnio, Joana | |
dc.contributor.author | Roberto, VĂąnia | |
dc.contributor.author | Andrade, Raquel | |
dc.contributor.author | Calado, Sofia | |
dc.contributor.author | Faleiro, Maria Leonor | |
dc.contributor.author | Albuquerque Andrade de Matos, Carlos Adriano | |
dc.contributor.author | Marques, Nuno | |
dc.contributor.author | Marreiros, Ana | |
dc.contributor.author | Nzwalo, HipĂłlito | |
dc.contributor.author | Pais, Sandra | |
dc.contributor.author | Palmeirim, Isabel | |
dc.contributor.author | SimĂŁoa, SĂłnia | |
dc.contributor.author | Joaquim, Natércia | |
dc.contributor.author | Miranda, Rui | |
dc.contributor.author | PĂȘgas, AntĂłnio | |
dc.contributor.author | Raposo, Daniela Marques | |
dc.contributor.author | Sardo, Ana | |
dc.contributor.author | AraĂșjo, InĂȘs | |
dc.contributor.author | Nóbrega, Clévio | |
dc.contributor.author | Castelo-Branco, Pedro | |
dc.contributor.author | Bragança, José | |
dc.date.accessioned | 2024-12-16T11:53:46Z | |
dc.date.available | 2024-12-16T11:53:46Z | |
dc.date.issued | 2024-12 | |
dc.description.abstract | Human induced pluripotent stem cells (hiPSCs) hold promises to model and understand human diseases, including those associated with ageing. Here, we describe ABCRIi001-A, a hiPSC line generated from peripheral blood mononuclear cells (PBMCs) of a 79-year-old female enrolled in a study for development of an ageing score (ALFA Score). PBMCs were reprogrammed using three Sendai virus-based reprogramming vectors (hKOS, hc-Myc, and hKlf4). ABCRIi001-A showed normal morphology and karyotype, viral clearance, absence of genomic aberrations, and their pluripotency was confirmed by expression of pluripotency-related markers and their ability to differentiate into the three germ layers. ABCRIi001-A is valuable for ageing-related studies. | eng |
dc.description.sponsorship | ALG-01-0145-FEDER-072586 | |
dc.identifier.doi | 10.1016/j.scr.2024.103576 | |
dc.identifier.issn | 1873-5061 | |
dc.identifier.uri | http://hdl.handle.net/10400.1/26482 | |
dc.language.iso | eng | |
dc.peerreviewed | yes | |
dc.publisher | Elsevier | |
dc.relation.ispartof | Stem Cell Research | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.title | Establishment of an induced pluripotent cell line (ABCRIi001-A) from an elderly female for ageing research | eng |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.citation.startPage | 103576 | |
oaire.citation.title | Stem Cell Research | |
oaire.citation.volume | 81 | |
oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
person.familyName | Esteves | |
person.familyName | Vilhena Catarino Brito | |
person.familyName | Rajado | |
person.familyName | Silva | |
person.familyName | ApolĂłnio | |
person.familyName | Roberto | |
person.familyName | Andrade | |
person.familyName | Calado | |
person.familyName | Faleiro | |
person.familyName | Albuquerque Andrade de Matos | |
person.familyName | Marques | |
person.familyName | Marreiros | |
person.familyName | Nzwalo | |
person.familyName | Pais | |
person.familyName | Palmeirim | |
person.familyName | Joaquim | |
person.familyName | NĂłbrega | |
person.familyName | Castelo-Branco | |
person.familyName | Bragança | |
person.givenName | Filipa | |
person.givenName | David | |
person.givenName | Ana Teresa | |
person.givenName | NĂĄdia | |
person.givenName | Joana | |
person.givenName | VĂąnia | |
person.givenName | Raquel | |
person.givenName | Sofia | |
person.givenName | Maria Leonor | |
person.givenName | Carlos Adriano | |
person.givenName | Nuno | |
person.givenName | Ana | |
person.givenName | HipĂłlito | |
person.givenName | Sandra | |
person.givenName | Isabel | |
person.givenName | Natércia | |
person.givenName | Clévio | |
person.givenName | Pedro | |
person.givenName | José | |
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