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Temporal and spatial expression patterns of pregnane X receptor and vitamin K epoxide reductase genes, two core molecular players on fish vitamin K homeostasis and skeletal development.

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dc.contributor.authorFernández, Ignacio
dc.contributor.authorCancela, Leonor
dc.contributor.authorGavaia, Paulo J.
dc.date.accessioned2014-06-18T08:33:41Z
dc.date.available2014-06-18T08:33:41Z
dc.date.issued2012
dc.description.abstractVitamin K (VK) is a liposoluble vitamin known to be essential for bone metabolism by two different pathways: (i) by its role as a coenzyme in the gamma-carboxylation of some skeletal proteins (e.g. osteocalcin (OC) and matrix Gla protein (MGP); Price et al., 1998); and (ii) through its role in skeletal gene transcription via binding to the pregnane X receptor (PXR; Azuma et al., 2010).por
dc.description.sponsorshipPDTC-MAR-105152-2008
dc.identifier.citationFernandez I., Cancela M.L., Gavaia P.J. 2012. Temporal and spatial expression patterns of pregnane X receptor and vitamin K epoxide reductase genes, two core molecular players on fish vitamin K homeostasis and skeletal development.por
dc.identifier.otherAUT: LCA00739
dc.identifier.urihttp://hdl.handle.net/10400.1/4350
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherEuropean Aquaculture Society; World Aquaculture Societypor
dc.relationINTEGRATIVE ROLES OF VITAMIN K: NUTRITIONAL REQUIREMENTS FOR BETTER BONE DEVELOPMENT
dc.titleTemporal and spatial expression patterns of pregnane X receptor and vitamin K epoxide reductase genes, two core molecular players on fish vitamin K homeostasis and skeletal development.por
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleINTEGRATIVE ROLES OF VITAMIN K: NUTRITIONAL REQUIREMENTS FOR BETTER BONE DEVELOPMENT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F82049%2F2011/PT
oaire.citation.conferencePlacePragapor
oaire.citation.endPage346por
oaire.citation.startPage346por
oaire.citation.titleAqua 2012por
person.familyNameCancela
person.familyNameGavaia
person.givenNameM. Leonor
person.givenNamePaulo
person.identifier.ciencia-idB619-FC16-D007
person.identifier.orcid0000-0003-3114-6662
person.identifier.orcid0000-0002-9582-1957
person.identifier.ridA-6470-2011
person.identifier.scopus-author-id6507104377
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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relation.isProjectOfPublication.latestForDiscoveryc92313d2-71c0-4b43-9593-b689bf4396a3

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