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Immunohistochemical detection of estrogen receptors in fish scales

2009-01-01Journal article Restricted access
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dc.contributor.authorPinto, Patricia IS
dc.contributor.authorEstêvão, M. Dulce
dc.contributor.authorRedruello, Begoña
dc.contributor.authorSocorro, S.
dc.contributor.authorCanario, Adelino V. M.
dc.contributor.authorPower, Deborah
dc.date.accessioned2014-05-12T16:29:07Z
dc.date.available2014-05-12T16:29:07Z
dc.date.issued2009-01-01
dc.date.updated2014-05-08T10:46:00Z
dc.description.abstractCalcium mobilization from internal stores, such as scales, induced by 17b-estradiol during sexual maturation in salmonids is well documented. This calcium mobilization from scales is proposed to be mediated by the estrogen receptor (ER). However, the ER subtypes involved and signaling mechanisms responsible for this effect remain to be fully characterized. In the present study, we have localized ERa, ERba and ERbb proteins in juvenile and adult sea bream (Sparus auratus) and Mozambique tilapia (Oreochromis mossambicus) scales by immunohistochemistry with sea bream ER subtype specific antibodies. The three ERs were detected in isolated or small groups of round cells, in the basal layer of the scales of both juvenile and adult fish and the localization and signal intensity varied with the species and age of the animals. The ERs may be co-localized in cells of the scale posterior region that expressed tartrateresistant acid phosphatase (TRAP), a marker for osteoclasts. These results suggest that the calcium mobilizing action of 17b-estradiol on fish scales is via its direct action on ERs localized in osteoclasts.por
dc.identifier.citationPinto, P. I. S.; Estevao, M. D.; Redruello, B.; Socorro, S. M.; Canario, A. V. M.; Power, D. M.Immunohistochemical detection of estrogen receptors in fish scales, General and Comparative Endocrinology, 160, 1, 19-29, 2009.por
dc.identifier.doihttp://dx.doi.org/10.1016/j.ygcen.2008.10.011
dc.identifier.issn0016-6480
dc.identifier.otherAUT: MES00382; ACA00258; DPO00386
dc.identifier.urihttp://hdl.handle.net/10400.1/3870
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relation.publisherversionhttp://ac.els-cdn.com/S0016648008003705/1-s2.0-S0016648008003705-main.pdf?_tid=1f611f44-d9ee-11e3-b557-00000aacb35f&acdnat=1399910430_5b7601ad4824e3cdd2e02c262ab56d03por
dc.subjectEstrogen receptorpor
dc.subjectEstradiolpor
dc.subjectCalciumpor
dc.subjectOsteoclastpor
dc.subjectEsmaloid scalepor
dc.subjectTeleostpor
dc.titleImmunohistochemical detection of estrogen receptors in fish scalespor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage29por
oaire.citation.issue1por
oaire.citation.startPage19por
oaire.citation.titleGeneral and Comparative Endocrinologypor
oaire.citation.volume160por
person.familyNamePinto
person.familyNameEstêvão
person.familyNameRedruello
person.familyNameCanario
person.familyNamePower
person.givenNamePatricia IS
person.givenNameMaria Dulce da Mota Antunes de Oliveira
person.givenNameBegoña
person.givenNameAdelino
person.givenNameDeborah Mary
person.identifier643457
person.identifierI-4695-2014
person.identifier143624
person.identifier.ciencia-idE51D-5CCB-B1C6
person.identifier.ciencia-id881B-53E8-0DB1
person.identifier.ciencia-id1F1E-D3B3-F804
person.identifier.ciencia-id891A-8A44-3CAE
person.identifier.orcid0000-0001-7854-3898
person.identifier.orcid0000-0002-7151-8363
person.identifier.orcid0000-0003-1787-5594
person.identifier.orcid0000-0002-6244-6468
person.identifier.orcid0000-0003-1366-0246
person.identifier.ridM-3817-2013
person.identifier.ridC-7942-2009
person.identifier.scopus-author-id10240774300
person.identifier.scopus-author-id8381590400
person.identifier.scopus-author-id56568523700
person.identifier.scopus-author-id7101806760
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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