CCM2-Artigos (em revistas ou actas indexadas)
URI permanente para esta coleção:
Conteúdo: Artigos em revistas ou actas de conferências indexadas
a) incluídas na
a) incluídas na
- » Web of Science
- (v. www.webofknowledge.com)
- » ERIH
- (European Research Index for Humanities: erihplus)
- » Latindex
- (Sistema Regional de Información para Revistas Científicas de América Latina, Caribe, España y Portugal: latindex.org/latindex/)
- » Scielo
- (Scientific Electronic Library Online: www.scielo.org)
- » Scopus SJR
- (SCImago Journal & Country Rank: www.scimagojr.com)
Navegar
Percorrer CCM2-Artigos (em revistas ou actas indexadas) por autor "Aazza, Smail"
A mostrar 1 - 3 de 3
Resultados por página
Opções de ordenação
- Antioxidant activity and enzyme inhibitory potential of Euphorbia resinifera and E. officinarum honeys from Morocco and plant aqueous extractsPublication . Boutoub, Oumaima; EL-Geundouz, Soukaina; Estevinho, Leticia M.; Paula, Vanessa B.; Aazza, Smail; El Ghadraoui, Lahsen; Rodrigues, Brígida; Raposo, Sara; Carlier, Jorge; Costa, Maria Clara; Miguel, MariaNatural products may be applied in a wide range of domains, from agriculture to food and pharmaceutical industries. In this study, the antioxidant properties and the capacity to inhibit some enzymatic activities ofEuphorbia resiniferaandEuphorbia officinarumaqueous extracts and honeys were assessed. The physicochemical characteristics were also evaluated. Higher amounts of iron, copper and aluminium were detected inE. officinarumhoney, which may indicate environmental pollution around the beehives or inadequate storage of honey samples. This honey sample showed higher amounts of total phenols and better capacity for scavenging superoxide anion free radicals and DPPH free radicals as compared withE. resiniferahoney, but poorer capacity for inhibiting lipoxygenase, acetylcholinesterase, tyrosinase and xanthine oxidase. The ratio plant mass:solvent volume (1:100) and extraction time (1 - 2 h) were associated with higher total phenols and better antioxidant activities and lipoxygenase, acetylcholinesterase and tyrosinase inhibitory activities, regardless of the plant species. The aqueous extracts had systematically higher in vitro activities than the respective honey samples.
- Chemical characterization of volatile and non-volatile constituents of aqueous extracts from euphorbia officinarum and E. resinifera: influence of extraction conditions on antioxidant and α-glucosidase inhibitory activitiesPublication . BOUTOUB, OUMAIMA; El Ghadraoui, Lahsen; El-Guendouz, Soukaina; Aazza, Smail; Figueiredo, Ana Cristina; Silva, José Paulo da; Miguel, Maria da GraçaThis study performed a chemical characterization of Euphorbia officinarum and Euphorbia resinifera volatile and non-volatile aqueous extracts. It was also evaluated how extraction variables (extraction time and plant-tosolvent ratio, PSR) influenced the chemical composition and biological responses of the aqueous extracts of four populations of E. officinarum and one population of E. resinifera. The experimental results were fitted using second-order polynomial equations for all response variables. The volatiles (essential oils) were isolated by hydrodistillation and analyzed for quantification and component identification, by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS), respectively. The volatile fraction of E. officinarum contained higher percentages of oxygenated monoterpenes and phenylpropanoids, whereas palmitic acid predominated in E. resinifera. Liquid chromatography-mass spectrometry (LC-MS) was used to analyze the aqueous extract of both species and the tentatively annotated compounds included particularly flavonoids, coumarins, oxylipins, and aliphatic dicarboxylic acids. Two-way ANOVA and response surface methodology highlighted that PSR was generally the main factor affecting the measured responses, whereas the influence of extraction time was response- and population-dependent. In addition, Pearson correlation and principal component analyses showed that the in vitro biological activities were more dependent on phytochemical composition than on total phenolic content.
- Comparative study of the antioxidant and enzyme inhibitory activities of two types of Moroccan Euphorbia entire honey and their phenolic extractsPublication . Boutoub, Oumaima; EL-GUENDOUZ, Soukaina; Manhita, Ana; Dias, Cristina Barrocas; Estevinho, Letícia M.; Paula, Vanessa B.; Carlier, Jorge; Costa, Maria Clara; Rodrigues, Brígida; Raposo, Sara; Aazza, Smail; El Ghadraoui, Lahsen; Miguel, Maria GraçaHoney is a natural food product very famous for its health benefits for being an important source of antioxidant and phenolic compounds. Euphorbia honeys obtained from different regions of Morocco were evaluated for their ability to inhibit acetylcholinesterase, lipoxygenase, tyrosinase and xanthine oxidase activities. Their antioxidant properties were evaluated using the: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging capacity, nitric oxide scavenging activity (NO) and scavenging ability of superoxide anion radical. Then, the phenolic extracts of the same entire honey samples were evaluated by liquid chromatography coupled to diode array detection and mass spectrometry (LC-DAD-MS) and tested for the biological activities previously evaluated on the entire honeys, in order to conduct a comparative study between both (honey and phenolic extracts). The chromatographic profiles for the studied Euphorbia honey extracts were different. Phenolic compounds gallic acid, 4-hydroxybenzoic acid and p-coumaric acid were detected in all samples, whereas kampferol was only present in two samples. Physicochemical parameters and total phenolic content were also determined. Entire honey that recorded the highest rate of phenols was sample M6 (E. resinifera) = 69.25 mg GAE/100 g. On the other hand, the phenolic extracts had better antioxidant and enzyme inhibitory activities than the entire honeys, regardless the monofloral honey type. In conclusion, the studied Euphorbia honeys may have a great potential as antioxidant, anti-inflammatory and anti-tyrosinase sources for pharmaceutical and cosmetic applications.