FCT2-Artigos (em revistas ou actas indexadas)
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Percorrer FCT2-Artigos (em revistas ou actas indexadas) por Objetivos de Desenvolvimento Sustentável (ODS) "03:Saúde de Qualidade"
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- Adaptation and validation of the perceived restorativeness scale (PRS) for the portuguese population: a study on the assessment of the restorative effect of environmentsPublication . Sousa, Cátia; Silva Fernandes, Maria Jacinta; Encarnação, Tiago; Gonçalves, GabrielaThe relationship between natural environments and psychological well-being has gained increasing attention in environmental and health sciences. However, there is still a lack of robust quantitative instruments to assess the restorative potential of different environments. This study aimed to adapt and validate the Portuguese version of the Perceived Restorativeness Scale (PRS), an instrument based on Attention Restoration Theory that evaluates the perceived restorative qualities of environments. In Study 1, exploratory and confirmatory factor analyses were conducted on data from 410 participants. The results supported a refined 20-item version of the scale, comprising four factors—being away, fascination, compatibility, and legibility—with good internal consistency and acceptable model fit. Measurement invariance analysis confirmed configural, metric, and scalar invariance across gender. In Study 2, a separate sample of 212 participants completed the PRS along with additional validated measures: the Sublime Emotion toward Nature Scale (SEN), an aesthetic evaluation of landscapes, and the Positive and Negative Affect Schedule (PANAS). The PRS showed strong convergent and discriminant validity and significantly predicted restorative outcomes. These findings support the psychometric adequacy of the Portuguese PRS and its relevance as a valid tool for assessing perceived restorativeness in both natural and built environments. The scale may inform future research and public policies aimed at designing spaces that promote psychological restoration and mental well-being.
- Advanced nanotherapeutic strategies transforming diabetic wound healingPublication . Ramos, Filipa; Kumar, Girish; Virmani, Tarun; Sharma, Abhishek; Duarte, Sofia O. D.; Fonte, PedroDue to their high recurrence rates and slow healing, diabetic wounds are becoming a greater public health concern [Citation1]. Each year, 1.6 million cases of diabetic wounds occur in the United States alone, affecting approximately 18.6 million people worldwide [Citation2]. Because of poor cellular regeneration, increased inflammation, and reduced angiogenesis, traditional treatments like debridement, antibiotics, and dressings usually do not work [Citation3]. To overcome the limitations of traditional treatments, there is now a significant demand for advanced therapeutic modalities that promise accurate, efficient, and rapid healing processes [Citation4]. These include microneedles (MNs), exosomes, tetrahedral framework nucleic acids (tFNAs), three-dimensional scaffolds, gene therapy, oxygen-releasing biomaterials, phototherapies, and nanozymes.
- Antibacterial, antioxidant, and antiproliferative activities of corymbia citriodora and the essential oils of eight eucalyptus speciesPublication . Miguel, Maria da Graça; Gago, Custódia; Estêvão, Maria Dulce da Mota Antunes de Oliveira ; Lagoas, Soraia; Faleiro, Maria Leonor; Megías, Cristina; Cortés-Giraldo, Isabel; Vioque, Javier; Figueiredo, Ana CristinaBackground: Essential oils (EOs) have shown antimicrobial, antioxidant, and antiproliferative activity, which may, alone or in combination with other substances, potentially be used for the development of new drugs. However, their chemical variability, depending on the species, varieties, or geographical origin (among other factors) determines different bioactivities that need to be evaluated. Methods: The antioxidant activity of Corymbia citriodora and eight Eucalyptus species EOs was determined using two different methods: the scavenging ability of 2,20 -azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS+• ) and peroxyl free radicals or oxygen radical absorbance capacity (ORAC). Antibacterial activity was evaluated using the microorganisms Streptococcus pneumoniae (strains D39 and TIGR4), and Haemophilus influenza (strain DSM 9999). The essential oils’ minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) was assessed using a microdilution method. The antiproliferative activity was determined using the THP-1 cell line (human acute monocytic leukaemia) with methylthiazolyldiphenyl-tetrazolium bromide assay (MTT). Results: Corymbia citriodora and Eucalyptus viminalis EOs showed the highest ABTS and peroxyl free radical scavenging capacity. Eucalyptus globulus EO showed a high potential to treat Streptococcus pneumoniae infections. Haemophilus influenzae was the respiratory pathogen that showed the highest resistance to all EOs, including tea tree EO. After 96 h of incubation, at 25 µg/mL, Eucalyptus radiata and Eucalyptus viminalis EOs showed highest cytotoxic activity against the THP-1 cell line. Conclusions: Despite their specific bioactivities, no single EO showed simultaneously good antioxidant, antimicrobial, and antiproliferative activity.
- Antimicrobial and antioxidant activities of natural compounds: enhance the safety and quality of foodPublication . Faleiro, Maria Leonor; Miguel, Maria da GraçaNature has offered us a tremendous diversity of natural compounds, for which antimicrobial and antioxidant properties have been intensively explored and nowadays are plenty recognized. During the last decades both the antimicrobial action of natural compounds (preventing and limiting microbial growth) and their antioxidant properties (reducing the oxidation of fats and limiting the ripening and browning of fruit and vegetables after harvesting) have been intensively investigated, particularly in the food packaging sector, evidencing that they may represent an effective eco-friendly approach to enhance the safety and quality of food products, without an environmentally deleterious impact.
- Antioxidant activity of myrtus communis l. and myrtus nivellei batt. & trab. extracts: a brief reviewPublication . Hennia, Aicha; Miguel, Maria da Graça; Nemmiche, SaidMyrtus communis L. (myrtle) and Myrtus nivellei Batt. & Trab. (Saharan myrtle) have been used in folk medicine for alleviating some ailments. M. communis is largely distributed in the Mediterranean Basin, whereas M. nivellei is confined in specific zones of the central Saharan mountains. The chemical composition and antioxidant activity of berry and leaf extracts isolated from myrtle are deeply documented, whereas those isolated from Saharan myrtle extracts are less studied. In both species, the major groups of constituents include gallic acid derivatives, flavonols, flavonol derivatives, and hydroxybenzoic acids. In coloured berries, anthocyanins are also present. In M. nivellei extracts are reported for some compounds not described in M. communis so far: 2-hydroxy-1,8-cineole-β-D-glucopyranoside, 2-hydroxy-1,8-cineole 2-O-α-L-arabinofuranosyl (1→6)-β-D-glucopyranoside, rugosin A, and rugosin B. Berries and leaves extracts of both species had antioxidant activity. Comparative studies of the antioxidant activity between leaf and berry myrtle extracts revealed that leaf extracts are best antioxidants, which can be assigned to the galloyl derivatives, flavonols, and flavonols derivatives, although the ratio of these groups of compounds might also have an important role in the antioxidant activity. The anthocyanins present in myrtle berries seem to possess weak antioxidant activity. The antioxidant activity of sample extracts depended on various factors: harvesting time, storage, extraction solvent, extraction type, and plant part used, among other factors. Leaf extracts of myrtle revealed to possess anti-inflammatory activity in several models used. This property has been attributed either to the flavonoids and/or hydrolysable tannins, nevertheless nonprenylated acylphloroglucinols (e.g., myrtucommulone and semimyrtucommulone) have also revealed a remarkable role in that activity. The biological activities of myrtle extracts found so far may direct its use towards for stabilizing complex lipid systems, as prebiotic in food formulations, and as novel therapeutic for the management of inflammation.
- Embedding a real-time strawberry detection model into a pesticide-spraying mobile robot for greenhouse operationPublication . Amraoui, Khalid El; Ansari, Mohamed El; Lghoul, Mouataz; Alaoui, Mustapha El; Abanay, Abdelkrim; Jabri, Bouazza; Masmoudi, Lhoussaine; LUÍS VALENTE DE OLIVEIRA, JOSÉAbstract: The real-time detection of fruits and plants is a crucial aspect of digital agriculture, enhancing farming efficiency and productivity. This study addresses the challenge of embedding a real-time strawberry detection system in a small mobile robot operating within a greenhouse environment. The embedded system is based on the YOLO architecture running in a single GPU card, with the Open Neural Network Exchange (ONNX) representation being employed to accelerate the detection process. The experiments conducted in this study demonstrate that the proposed model achieves a mean average precision (mAP) of over 97%, processing eight frames per second for 512 × 512 pixel images. These results affirm the utility of the proposed approach in detecting strawberry plants in order to optimize the spraying process and avoid inflicting any harm on the plants. The goal of this research is to highlight the potential of integrating advanced detection algorithms into small-scale robotics, providing a viable solution for enhancing precision agriculture practices.
- The growth curve method to rapidly derive the antibacterial potential of polyoxovanadatesPublication . Marques-da-Silva, Dorinda; Mal, Sib Sankar; Aureliano, Manuel; Lagoa, RicardoIn previous studies (Marques-da-Silva et al., 2019), we measured the minimum inhibitory concentrations (MICs) of three polyoxovanadates, namely V10, MnV11, and MnV13, against Escherichia coli. MICs were obtained following the standard method, which requires a 16–20 h culture and might neglect the effects of the compounds’ metabolism during incubation. In this work, we studied the action of those compounds against Enterococcus faecalis by monitoring the bacterial growth kinetics, and we observed that the inhibition was evident from the beginning of the exponential phase. Notably, data collected from just a 7 h culture was enough to identify the compounds with stronger antibacterial activity according to standard MICs.
- HVAC systems applied in university buildings with control based on PMV and aPMV indexesPublication . Conceição, Eusébio; Sousa, António F. M.; Gomes, João; Ruano, AntonioIn this work, HVAC (Heating, Ventilation and Air Conditioning) systems applied in university buildings with control based on PMV (Predicted Mean Vote) and aPMV (adaptive Predicted Mean Vote) indexes are discussed. The building’s thermal behavior with complex topology, in transient thermal conditions, for summer and winter conditions is simulated by software. The university building is divided into 124 spaces, on two levels with an area of 5931 m2 , and is composed of 201 transparent surfaces and 1740 opaque surfaces. There are 86 compartments equipped with HVAC systems. The simulation considers the actual occupation and ventilation cycles, the external environmental variables, the internal HVAC system and the occupants’ and building’s characteristics. In this work, a new HVAC control system, designed to simultaneously obtain better occupants’ thermal comfort levels according to category C of ISO 7730 with less energy consumption, is presented. This new HVAC system with aPMV index control is numerically implemented, and its performance is compared with the performance of the same HVAC system with the usual PMV index control. Both HVAC control systems turn on only when the PMV index or the aPMV index reaches values below −0.7, in winter conditions, and when the PMV index or the aPMV index reaches values above +0.7, in summer conditions. In accordance with the results obtained, the HVAC system guarantees negative PMV and aPMV indexes in winter conditions and positive PMV and aPMV indexes in summer conditions. The energy consumption level is higher in winter conditions than in summer conditions for compartments with shading, and it is lower in winter conditions than in summer conditions for compartments exposed to direct solar radiation. The consumption level is higher using the PMV control than with the aPMV control. Air temperature, in accordance with Portuguese standards, is higher than 20 ◦C in winter conditions and lower than 27 ◦C in summer conditions. In Mediterranean climates, the HVAC systems with aPMV control provide better occupants’ thermal comfort levels and less energy consumption than the HVAC system with PMV control.
- LINA: an augmented reality social game enhancing sense of belonging among classmates: an uncontrolled pre-post evaluation studyPublication . Krammer, Ina; Mittmann, Gloria; Nater, Urs M.; Barnard, Adam; Martins, Diogo; Dias, João; Schrank, Beate; Woodcock, Kate A.Supportive peer relationships are fundamental in the development of well-being. Since early adolescents spend a lot of time at school, especially in their classroom, a sense of belonging among classmates plays a pivotal role for mental health and academic functioning. Programs that enhance sense of belonging among classmates through improving peer relationships in classrooms are rare. Given that early adolescents increasingly use digital media to establish and maintain relationships with classmates, there is potential in digital social games that enhance social connectivity and collaboration, especially during the difficult transition from primary to secondary school. LINA ('Lina Is Not Alone') is a novel social augmented reality game for classrooms that is designed to enhance sense of belonging among classmates through improving their relationships with classmates. We conducted an uncontrolled pre-post evaluation study to evaluate (a) player experience, (b) translation of the theory-led LINA design into user experience and (c) increases in sense of belonging after engagement with LINA. In total, data from 99 participants (Mage = 10.94; range = 10-12; 51 girls, 48 boys) were included in this study. Our results provided evidence for (a) high satisfaction and acceptability of LINA, (b) a successful translation of theory-led design features into user experiences, and (c) increases in sense of belonging. We discuss practical implications and future development of LINA.
- Linguistic loops and geometric invariants as a way to pre-verbal thought?Publication . Corradetti, Daniele; Alessio MarraniWe introduce the concepts of linguistic transformation, linguistic loop and semantic deficit. By exploiting Lie group theoretical and geometric techniques, we define invariants that capture the structural properties of a whole linguistic loop. This result paves the way to a totally new line of research, employing tools from Lie theory and higher-dimensional geometry within language studies. But, even more intriguingly, our study hints to a mathematical characterization of the meta-linguistic or pre-verbal thought, namely of those cognitive structures that precede the language.