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Editorial: advancing cancer therapy: innovative strategies targeting immune evasion and metabolic modulation

dc.contributor.authorTeotónio Fernandes, Mónica Alexandra
dc.contributor.authorDe Sousa-Coelho, Ana Luísa
dc.contributor.authorMéndez-Lucas, Andrés
dc.date.accessioned2025-10-04T08:45:54Z
dc.date.available2025-10-04T08:45:54Z
dc.date.issued2025-08-29
dc.description.abstractCancer remains one of the leading causes of death worldwide, with both incidence and mortality continuing to rise despite advances in diagnosis and treatment (1). While early-stage cancers often respond to conventional therapies, advanced and recurrent tumors frequently develop resistance, limiting long-term therapeutic efficacy (2).Two fundamental hallmarks of cancer, immune evasion and metabolic reprogramming, enable tumors to thrive in hostile microenvironments (3, 4). Although immunotherapies have revolutionized cancer care, a significant proportion of patients either fail to respond or acquire resistance over time (5). In parallel, altered tumor metabolism is increasingly recognized as a promising therapeutic target, particularly for enhancing responses to immunotherapy (7).This Research Topic highlights recent advances that move beyond traditional treatment. Collectively, the nine featured articles provide valuable insights into the interplay between immunity and metabolism in cancer, exploring strategies to overcome therapeutic resistance and improve clinical outcomes across diverse cancer types.eng
dc.identifier.doi10.3389/fmed.2025.1677300
dc.identifier.issn2296-858X
dc.identifier.urihttp://hdl.handle.net/10400.1/27789
dc.language.isoeng
dc.peerreviewedyes
dc.publisherFrontiers Media
dc.relation.ispartofFrontiers in Medicine
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCancer therapy
dc.subjectBiomarkers
dc.subjectImmunotherapy
dc.subjectMetabolism
dc.subjectTherapy resistance
dc.subjectPersonalized medicine
dc.titleEditorial: advancing cancer therapy: innovative strategies targeting immune evasion and metabolic modulationeng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFrontiers in Medicine
oaire.citation.volume12
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameTeotónio Fernandes
person.familyNameDe Sousa-Coelho
person.givenNameMónica Alexandra
person.givenNameAna Luísa
person.identifier.ciencia-idD21D-88F0-DBD1
person.identifier.ciencia-id691B-A574-28ED
person.identifier.orcid0000-0002-1206-1367
person.identifier.orcid0000-0002-8451-4302
relation.isAuthorOfPublication4aeefcfb-528b-4067-95ed-fef9aacccebf
relation.isAuthorOfPublicationc7b0d14f-ae71-45a3-bce1-6dcd1fc66f67
relation.isAuthorOfPublication.latestForDiscovery4aeefcfb-528b-4067-95ed-fef9aacccebf

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