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Distribution and cellular localization of sea bream estrogen receptors in calcified tissues
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In teleost fish, estradiol has been shown to induce calcium mobilization from internal stores, in particular the scales. In the present study, we have localized the estrogen receptor proteins (α, βa and βb) in the scales of juvenile and adult sea bream, using immunohistochemistry with ER isoform-specific antibodies. The ERs co-localized in cells of the scale posterior region that also expressed TRACP, the putative osteoclasts. These results suggest that the calcium mobilising action of estradiol on fish scales is via its direct action on osteoclasts.
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Pinto, P.; Estêvão, M. D.; Redruello, B.; Power, D. M.; Canário, A. V. M. – Distribution and Cellular localization of Sea Bream Estrogen Receptors in Calcified Tissues, 5º Congresso da Associação Ibérica de Endocrinologia Comparada, 8-10/9/2005, Faro.