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Gene expression during regeneration of zebrafish (danio rerio) fins: relative expression levels of mineralization–related gla proteins

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Most animals have the ability to regenerate epidermal injuries yet only a few can regenerate largely severed appendages that comprise several different tissues. Nowadays zebrafish is one of the most used metazoan models in regeneration studies in particular for investigation of molecular events during fin regeneration process. Fin regeneration starts through the formation of a blastema, a set of heterogeneous mesenchyma-like cells located between stump tissues and the wounded epidermis. This event, denominated epimorphic regeneration, comprises strict growth control and cell reprogramming leading to faithful restoration of the lost parts.

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8. Brito A.B., P.J. Gavaia, M.L. Cancela 2007. Gene expression during regeneration of zebrafish (danio rerio) fins: relative expression levels of mineralization–related gla proteins. Meeting of European COST B23 Action "Oral Development and Regeneration”, May 30th- June 3rd, Barcelona, Spain

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Universitat de Barcelona

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